Title : Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding.

Pub. Date : 2017 Dec 21

PMID : 29225033






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we report a unique mechanism underlying the GOF of p53-R249S (p53-RS), a p53 mutant frequently detected in human hepatocellular carcinoma (HCC) that is highly related to hepatitis B infection and aflatoxin B1. Aflatoxin B1 tumor protein p53 Homo sapiens
2 Here we report a unique mechanism underlying the GOF of p53-R249S (p53-RS), a p53 mutant frequently detected in human hepatocellular carcinoma (HCC) that is highly related to hepatitis B infection and aflatoxin B1. Aflatoxin B1 tumor protein p53 Homo sapiens
3 Here we report a unique mechanism underlying the GOF of p53-R249S (p53-RS), a p53 mutant frequently detected in human hepatocellular carcinoma (HCC) that is highly related to hepatitis B infection and aflatoxin B1. Aflatoxin B1 tumor protein p53 Homo sapiens