Estradiol

cytochrome P450 family 1 subfamily A member 1 ; Homo sapiens







59 Article(s)
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Pub. Year
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1 33023449 The Activation of Procarcinogens by CYP1A1/1B1 and Related Chemo-Preventive Agents: A Review. 2021 1
2 32781018 Tryptophan and kynurenine stimulate human decidualization via activating Aryl hydrocarbon receptor: Short title: Kynurenine action on human decidualization. 2020 Sep 1
3 30680817 Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1-mediated carcinogenic estradiol metabolite formation. 2019 Apr 4
4 31147316 Nitidine Chloride-Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism. 2019 Aug 1
5 31374317 Bisphenol A affects estradiol metabolism by targeting CYP1A1 and CYP19A1 in human placental JEG-3 cells. 2019 Dec 3
6 30184270 Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types. 2018 Dec 1
7 28334509 Disturbed testicular expression of the estrogen-metabolizing enzymes CYP1A1 and COMT in infertile men with primary spermatogenic failure: possible negative implications on Sertoli cells. 2017 May 1
8 28618207 Effect of dioxin and 17β-estradiol on the expression of cytochrome P450 1A1 gene via an estrogen receptor dependent pathway in cellular and xenografted models. 2017 Oct 1
9 26798414 Epistatic Interaction of CYP1A1 and COMT Polymorphisms in Cervical Cancer. 2016 1
10 27285958 Cigarette smoking and hormones. 2016 Aug 1
11 23700305 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breast cancer cells through alteration of CYP1A1 and CYP1B1 expression. 2015 May 1
12 25399436 Hyperoxia-induced changes in estradiol metabolism in postnatal airway smooth muscle. 2015 Jan 15 2
13 25678418 Regioselective hydroxylation of steroid hormones by human cytochromes P450. 2015 May 1
14 24528081 Preferential induction of CYP1A1 over CYP1B1 in human breast cancer MCF-7 cells after exposure to berberine. 2014 1
15 25257533 Defining molecular sensors to assess long-term effects of pesticides on carcinogenesis. 2014 Sep 25 1
16 23448447 Breast cancer and flavonoids - a role in prevention. 2013 1
17 23828038 Estrogen receptor α can selectively repress dioxin receptor-mediated gene expression by targeting DNA methylation. 2013 Sep 1
18 23842721 Clinical effects of A4889G and T6235C polymorphisms in cytochrome P-450 CYP1A1 for breast cancer patients treated with tamoxifen: implications for tumor aggressiveness and patient survival. 2013 Sep 1
19 20883830 Inhibition of 17β-estradiol activation by CYP1A1: genotype- and regioselective inhibition by St. John's Wort and several natural polyphenols. 2011 Jan 2
20 21513769 Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells. 2011 Jul 11 1
21 22384629 Importance of CYP1A1 polymorphism and its transcriptional regulation in ovarian and endometrial cancer. 2011 Dec 1
22 19365803 Differential action of chlorinated polycyclic aromatic hydrocarbons on aryl hydrocarbon receptor-mediated signaling in breast cancer cells. 2010 Apr 1
23 19833205 A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. 2010 Jan 1
24 20462226 A 3D model of CYP1B1 explains the dominant 4-hydroxylation of estradiol. 2010 Jun 28 3
25 20881610 Estrogens and development of pulmonary hypertension: interaction of estradiol metabolism and pulmonary vascular disease. 2010 Dec 1
26 21121773 Genetic polymorphisms in sex hormone metabolizing genes and drug response in women with epilepsy. 2010 Nov 2
27 19470599 Estrogen receptor subtype- and promoter-specific modulation of aryl hydrocarbon receptor-dependent transcription. 2009 Jun 3
28 17919675 Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. 2008 Feb 1 1
29 17440990 Inhibition of human recombinant cytochromes P450 CYP1A1 and CYP1B1 by trans-resveratrol methyl ethers. 2007 May 1
30 17570247 Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. 2007 Jul 2
31 16949219 Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. 2006 Oct 25 1
32 16949388 CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal. 2006 Sep 2
33 15507517 Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. 2005 Jan 3
34 15805301 Association of CYP1A1 polymorphisms with differential metabolic activation of 17beta-estradiol and estrone. 2005 Apr 1 1
35 15837795 ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. 2005 Jun 3 2
36 15867368 Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis. 2005 May 1 2
37 15964790 Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. 2005 Jul 1
38 16112414 Cytochrome P450-mediated metabolism of estrogens and its regulation in human. 2005 Sep 28 1
39 16207128 A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio. 2005 1
40 15050414 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells. 2004 Apr 1 1
41 15142886 Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. 2004 Oct 2
42 15157572 Effects of zearalenone on mRNA expression and activity of cytochrome P450 1A1 and 1B1 in MCF-7 cells. 2004 Jun 1
43 15377160 In vitro model of mammary estrogen metabolism: structural and kinetic differences between catechol estrogens 2- and 4-hydroxyestradiol. 2004 Sep 2
44 15521013 Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. 2004 Nov 1
45 12624000 CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs. 2003 Mar 2
46 12810639 Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1. 2003 Jun 15 2
47 12865317 Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. 2003 Aug 1
48 12902195 Effects of several dioxin-like compounds on estrogen metabolism in the malignant MCF-7 and nontumorigenic MCF-10A human mammary epithelial cell lines. 2003 Aug 1 2
49 12970067 Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. 2003 Dec 1
50 11921196 Neoplastic transformation of human breast epithelial cells by estrogens and chemical carcinogens. 2002 1