Pub. Date : 2015 Jan 15
PMID : 25399436
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pharmacological studies indicated that these effects were attributable to upregulation of CYP1a1 and subsequent increased metabolism of estradiol to a downstream intermediate 2-methoxyestradiol. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 2 | Our novel results on estradiol metabolism in fetal and early postnatal lung in the context of hyperoxia indicate CYP1a1 as a potential mechanism for the protective effect of estradiol in hyperoxia-exposed immature lung, which may help explain the sex difference in neonatal lung diseases. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |