Pub. Date : 2019 Apr
PMID : 30680817
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human cytochrome P450 1B1 (CYP1B1)-mediated formation of 4-hydroxyestradiol (4-OHE2) from 17beta-estradiol plays an important role in the progression of human breast cancer, while the biotransformation of 17beta-estradiol to 2-hydroxyestradiol mediated by cytochrome P450 1A1 (CYP1A1) is considered as a less harmful pathway. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 2 | Human cytochrome P450 1B1 (CYP1B1)-mediated formation of 4-hydroxyestradiol (4-OHE2) from 17beta-estradiol plays an important role in the progression of human breast cancer, while the biotransformation of 17beta-estradiol to 2-hydroxyestradiol mediated by cytochrome P450 1A1 (CYP1A1) is considered as a less harmful pathway. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 3 | Human cytochrome P450 1B1 (CYP1B1)-mediated formation of 4-hydroxyestradiol (4-OHE2) from 17beta-estradiol plays an important role in the progression of human breast cancer, while the biotransformation of 17beta-estradiol to 2-hydroxyestradiol mediated by cytochrome P450 1A1 (CYP1A1) is considered as a less harmful pathway. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |
| 4 | Human cytochrome P450 1B1 (CYP1B1)-mediated formation of 4-hydroxyestradiol (4-OHE2) from 17beta-estradiol plays an important role in the progression of human breast cancer, while the biotransformation of 17beta-estradiol to 2-hydroxyestradiol mediated by cytochrome P450 1A1 (CYP1A1) is considered as a less harmful pathway. | Estradiol | cytochrome P450 family 1 subfamily A member 1 | Homo sapiens |