Title : Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells.

Pub. Date : 2003 Dec

PMID : 12970067






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cytochrome P450 (CYP)1A1 and CYP1B1, which are under the regulatory control of the aryl hydrocarbon (Ah) receptor (AhR), catalyze the metabolic activation of numerous procarcinogens and the hydroxylation of 17beta-estradiol (E2) at the C-2 and C-4 positions, respectively. Estradiol cytochrome P450 family 1 subfamily A member 1 Homo sapiens