Title : Preferential induction of CYP1A1 over CYP1B1 in human breast cancer MCF-7 cells after exposure to berberine.

Pub. Date : 2014

PMID : 24528081






1 Functional Relationships(s)
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1 17beta-estradiol (E2), the main steroidal estrogen present in women, is metabolized via two major pathways: formation of the 2-hydroxyestradiol (2-OH E2) and 4-hydroxyestradiol (4-OH E2) through the action of Cytochrome P450 (CYP) 1A1 and 1B1, respectively. Estradiol cytochrome P450 family 1 subfamily A member 1 Homo sapiens