Guanosine Triphosphate

HRas proto-oncogene, GTPase ; Homo sapiens







190 Article(s)
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Pub. Year
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51 18758236 Mechanisms of Ras membrane organization and signalling: Ras on a rocker. 2008 Sep 1 1
52 18771285 Global conformational dynamics in ras. 2008 Sep 30 1
53 17497936 X-ray crystal structures reveal two activated states for RhoC. 2007 Jun 5 1
54 16481401 The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology. 2006 May 1
55 16488996 Ras and its signals diffuse through the cell on randomly moving nanoparticles. 2006 Feb 15 1
56 16569214 Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity. 2006 Jul 15 1
57 16895916 Phospholipase C epsilon suppresses integrin activation. 2006 Oct 6 1
58 16980621 Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling. 2006 Oct 1
59 15789417 Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants. 2005 May 15 2
60 15812354 Transient activation of Ras-dependent signalling at the early stages of Herbimycin A induced erythroid differentiation of human K562 cells. 2005 Mar 2
61 15860728 Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation. 2005 May 1 4
62 16024806 Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. 2005 Aug 4
63 14978301 Rapid evolution in conformational space: a study of loop regions in a ubiquitous GTP binding domain. 2004 Mar 1
64 15254246 Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. 2004 Aug 5
65 15287738 pH-dependent perturbation of Ras-guanine nucleotide interactions and Ras guanine nucleotide exchange. 2004 Aug 10 1
66 15355981 Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells. 2004 Nov 19 3
67 12569357 An unusual H-Ras mutant isolated from a human multiple myeloma line leads to transformation and factor-independent cell growth. 2003 Feb 6 1
68 11906819 Prenylcysteine carboxymethyltransferase type III activity is decreased in retinoic acid-treated SH-SY5Y neuroblastoma cells. 2002 May 1
69 12006650 Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. 2002 May 1
70 12032842 Insulin restores differentiation of Ras-transformed C2C12 myoblasts by inducing NF-kappaB through an AKT/P70S6K/p38-MAPK pathway. 2002 May 23 1
71 12149263 Galectin-1 augments Ras activation and diverts Ras signals to Raf-1 at the expense of phosphoinositide 3-kinase. 2002 Oct 4 1
72 12359913 Insider information: how palmitoylation of Ras makes it a signaling double agent. 2002 Oct 1 1
73 11179219 Phospholipase C(epsilon): a novel Ras effector. 2001 Feb 15 2
74 11283610 GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. 2001 Apr 4
75 11309191 Compartmentalization of Ras proteins. 2001 May 1
76 11313946 A novel potential effector of M-Ras and p21 Ras negatively regulates p21 Ras-mediated gene induction and cell growth. 2001 Jan 11 1
77 11593050 Identification of cell signaling molecules by expression cloning. 2001 Oct 9 2
78 11676197 The upregulation by peplomycin of signal transduction in human cells. 2001 Sep 1
79 11188692 Structural changes induced in p21Ras upon GAP-334 complexation as probed by ESEEM spectroscopy and molecular-dynamics simulation. 2000 Dec 15 1
80 10208427 Isoform-specific insertion near the Grb2-binding domain modulates the intrinsic guanine nucleotide exchange activity of hSos1. 1999 Mar 4 1
81 10453987 Insulin-like growth factor I activates insulin receptor substrate 1 and Ras in human osteosarcoma cells. 1999 1
82 10595559 2'Halo-ATP and -GTP analogues: rational phasing tools for protein crystallography. 1999 Nov 1
83 10607402 Display of Ras on filamentous phage through cysteine replacement. 1999 Dec 3
84 9405284 Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function. 1998 Jan 1 1
85 9437002 The putative "switch 2" domain of the Ras-related GTPase, Rab1B, plays an essential role in the interaction with Rab escort protein. 1998 Jan 1
86 9516156 Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5. 1998 Apr 1 2
87 9545299 Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. 1998 Apr 17 1
88 9619634 Contrasting levels of p21ras activation and expression of neurofibromin in peripheral primitive neuroectodermal tumour and neuroblastoma cells, and their response to retinoic acid. 1998 May 7 3
89 9620547 Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain. 1998 May 7 1
90 9760267 Transient kinetic studies on the interaction of Ras and the Ras-binding domain of c-Raf-1 reveal rapid equilibration of the complex. 1998 Oct 6 3
91 9778365 The role of ligand binding in the kinetic folding mechanism of human p21(H-ras) protein. 1998 Oct 20 1
92 9780005 Prolonged vs transient roles for early cell cycle signaling components. 1998 Aug 20 1
93 9102473 The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+. 1997 Mar 7 3
94 9112423 Hyperinsulinemia potentiates activation of p21Ras by growth factors. 1997 May 1
95 9312017 Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS. 1997 Sep 15 1
96 9345266 GTP loading of farnesylated p21Ras by insulin at the plasma membrane. 1997 Oct 9 3
97 9404480 RAS and the myelodysplastic syndromes. 1997 Sep 1
98 8626511 The differential effects of the Gly-60 to Ala mutation on the interaction of H-Ras p21 with different downstream targets. 1996 Apr 5 5
99 8636102 Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. 1996 Mar 22 1
100 8710888 Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav. 1996 Aug 6 1