Title : Hyperinsulinemia potentiates activation of p21Ras by growth factors.

Pub. Date : 1997 May

PMID : 9112423






1 Functional Relationships(s)
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1 Cells preincubated with 100 nM insulin for 24 or 48 hours exhibited further 5-8 fold increases in p21Ras.GTP loading in response to an acute (10 minute) challenge with either insulin, EGF, or IGF-1. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens