Title : Clustering of raft-associated proteins in the external membrane leaflet modulates internal leaflet H-ras diffusion and signaling.

Pub. Date : 2006 Oct

PMID : 16980621






1 Functional Relationships(s)
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1 Thus, clustering raft-associated HA proteins facilitated the early step whereby H-Ras is converted to an activated, GTP-loaded state but inhibited the ensuing step of downstream signaling via the Mek/Erk pathway. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens