| 101 |
8740369 | Electrostatic control of GTP and GDP binding in the oncoprotein p21ras. | 1996 Apr 15 |
5 |
| 102 |
8756686 | Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP. | 1996 Aug 13 |
1 |
| 103 |
8765045 | Distinct mechanisms mediate SHC association with the activated and resting B cell antigen receptor. | 1996 Aug |
1 |
| 104 |
8798525 | Purification of a protein palmitoyltransferase that acts on H-Ras protein and on a C-terminal N-Ras peptide. | 1996 Sep 20 |
1 |
| 105 |
8916907 | Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras. | 1996 Nov 12 |
3 |
| 106 |
8916908 | Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems. | 1996 Nov 12 |
1 |
| 107 |
8974153 | Ha-ras in normal and tumoral tissues: structure, function and regulation. | 1996 Sep |
1 |
| 108 |
7492562 | Kinetics of inorganic phosphate release during the interaction of p21ras with the GTPase-activating proteins, p120-GAP and neurofibromin. | 1995 Nov 28 |
2 |
| 109 |
7542586 | Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. | 1995 Jul 3 |
4 |
| 110 |
7559502 | Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors. | 1995 Oct 6 |
2 |
| 111 |
7576990 | p21ras: an oncoprotein functioning in growth factor-induced signal transduction. | 1995 Jul-Aug |
2 |
| 112 |
7592690 | Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation. | 1995 Oct 27 |
1 |
| 113 |
7608150 | Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless. | 1995 Jul 7 |
1 |
| 114 |
7613138 | The interleukin-5/receptor interaction activates Lyn and Jak2 tyrosine kinases and propagates signals via the Ras-Raf-1-MAP kinase and the Jak-STAT pathways in eosinophils. | 1995 May-Jun |
1 |
| 115 |
7706235 | Nitric oxide-stimulated guanine nucleotide exchange on p21ras. | 1995 Mar 31 |
2 |
| 116 |
7719852 | Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins. | 1995 Jan |
4 |
| 117 |
7737275 | T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras. | 1995 Apr |
1 |
| 118 |
7819254 | Substrate and product structural requirements for binding of nucleotides to H-ras p21: the mechanism of discrimination between guanosine and adenosine nucleotides. | 1995 Jan 17 |
1 |
| 119 |
7819259 | Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. | 1995 Jan 17 |
1 |
| 120 |
7880841 | Mutagenesis of the H-ras p21 at glycine-60 residue disrupts GTP-induced conformational change. | 1995 Mar 14 |
4 |
| 121 |
21153201 | Mechanism of activation of guanine nucleotide exchange factor by insulin. | 1995 Jul |
2 |
| 122 |
7787254 | Biological activity of human N-ras and K-ras genes containing the Asn17 dominant negative mutation. | 1994 |
1 |
| 123 |
7806540 | A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation. | 1994 Dec 30 |
6 |
| 124 |
7926013 | Epidermal growth factor induces protein tyrosine phosphorylation and association of p190 with ras-GTP-ase activating protein in Caco-2 cells. | 1994 Oct 10 |
1 |
| 125 |
7949098 | Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras. | 1994 Nov 15 |
2 |
| 126 |
8019003 | Raf-1 interferes with Ras and Rap1A effector functions in yeast. | 1994 Feb |
1 |
| 127 |
8073283 | Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. | 1994 Sep 2 |
2 |
| 128 |
8136358 | Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study. | 1994 Mar 22 |
1 |
| 129 |
8137813 | Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. | 1994 Mar 15 |
1 |
| 130 |
8144662 | Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. | 1994 Apr 8 |
4 |
| 131 |
8195713 | Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth. | 1994 Jun 1 |
1 |
| 132 |
15299412 | Crystallographic studies on p21(H-ras) using the synchrotron Laue method: improvement of crystal quality and monitoring of the GTPase reaction at different time points. | 1994 Jul 1 |
1 |
| 133 |
8245773 | p120 GAP requirement in normal and malignant human hematopoiesis. | 1993 Dec 1 |
1 |
| 134 |
8257693 | Solution dynamics of p21ras proteins bound with fluorescent nucleotides: a time-resolved fluorescence study. | 1993 Dec 14 |
1 |
| 135 |
8338834 | An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras. | 1993 Jul 27 |
5 |
| 136 |
8353139 | Role of GTPases and GTPase regulatory proteins in oncogenesis. | 1993 |
5 |
| 137 |
8376929 | p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes. | 1993 Oct 1 |
1 |
| 138 |
8386636 | Nucleotide binding and GTP hydrolysis by the 21-kDa product of the c-H-ras gene as monitored by proton-NMR spectroscopy. | 1993 Apr 15 |
2 |
| 139 |
8388384 | Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2. | 1993 May 25 |
1 |
| 140 |
8407889 | Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells. | 1993 Oct 5 |
2 |
| 141 |
8417322 | Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras. | 1993 Jan |
1 |
| 142 |
8423993 | Ras oncogene transformation of human B lymphoblasts is associated with lymphocyte activation and with a block of differentiation. | 1993 Jan |
1 |
| 143 |
8444185 | Epidermal-growth-factor receptors generate Ras.GTP more efficiently than insulin receptors. | 1993 Mar 1 |
1 |
| 144 |
8486615 | Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target. | 1993 May 5 |
3 |
| 145 |
8496156 | Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP hydrolysis on p21ras. | 1993 May 25 |
2 |
| 146 |
1321335 | GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion. | 1992 Aug |
2 |
| 147 |
1371879 | p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein. | 1992 Mar 1 |
1 |
| 148 |
1420142 | NMR studies of the conformational change in human N-p21ras produced by replacement of bound GDP with the GTP analog GTP gamma S. | 1992 Oct 27 |
4 |
| 149 |
1421163 | Three-dimensional structure of p21H-ras and its implications. | 1992 Aug |
1 |
| 150 |
1445214 | Interaction of GTPase-activating protein with p21ras, measured using a continuous assay for inorganic phosphate release. | 1992 Oct 15 |
2 |