Title : X-ray crystal structures reveal two activated states for RhoC.

Pub. Date : 2007 Jun 5

PMID : 17497936






1 Functional Relationships(s)
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1 Given that each of the nonhydrolyzable GTP analogues is able to promote the binding of RhoC to effector proteins, these results suggest that RhoC can undergo at least two conformational transitions during its conversion from a signaling-inactive to a signaling-active state, similar to what has recently been proposed for the H-Ras and M-Ras proteins. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens