Sulfonylurea Compounds

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







41 Article(s)
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1 34656068 CYP2C19 Loss-of-function Polymorphisms are Associated with Reduced Risk of Sulfonylurea Treatment Failure in Chinese Patients with Type 2 Diabetes. 2022 Feb 5
2 33731883 Pharmacogenetic-guided glimepiride therapy in type-2 diabetes mellitus: a cost-effectiveness study. 2021 Oct 2
3 33840516 Association Between the CYP2C9 Genotype and Hypoglycemia Among Patients With Type 2 Diabetes Receiving Sulfonylurea Treatment: A Meta-analysis. 2021 May 7
4 34194474 The Genetics of Adverse Drug Outcomes in Type 2 Diabetes: A Systematic Review. 2021 1
5 34429480 Impact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects. 2021 Aug 24 1
6 34900803 A pharmacogenetic pilot study of CYP2C9 common genetic variant and sulfonylureas therapeutic response in type 2 diabetes mellitus patients. 2021 Dec 5
7 31709648 The presence of two reduced function variants in CYP2C9 influences the acute response to glipizide. 2020 Dec 1
8 32406758 Inhibition of CYP2C9 by natural products: insight into the potential risk of herb-drug interactions. 2020 May 1
9 32504053 Pharmacogenetics of hypoglycemia associated with sulfonylurea therapy in usual clinical care. 2020 Dec 1
10 32575674 rs622342 in SLC22A1, CYP2C9*2 and CYP2C9*3 and Glycemic Response in Individuals with Type 2 Diabetes Mellitus Receiving Metformin/Sulfonylurea Combination Therapy: 6-Month Follow-Up Study. 2020 Jun 20 2
11 32606720 The Effect of CYP2C9 Genotype Variants in Type 2 Diabetes on the Pharmacological Effectiveness of Sulfonylureas, Diabetic Retinopathy, and Nephropathy. 2020 2
12 33612460 Pharmacogenetics of sulfonylurea: Presence of CYP2C9*2, CYP2C9*3 and a novel allele, CYP2C9*61, in Type 2 diabetes patients under sulfonylurea therapy. 2020 Jul 6
13 31086662 Frequency of CYP2C9 (*2, *3 and IVS8-109A>T) allelic variants, and their clinical implications, among Mexican patients with diabetes mellitus type 2 undergoing treatment with glibenclamide and metformin. 2019 May 2
14 27958378 Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. 2018 Jan 1
15 28656666 Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea-induced hypoglycaemia: A GoDARTS Study. 2018 Jan 4
16 26802434 Personalized medicine in diabetes: the role of 'omics' and biomarkers. 2016 Jun 1
17 27180666 [Pharmacogenetics of oral antidiabetic treatment]. 2016 Mar 1
18 27885968 Possible approaches to CYP2C9-guided prescription of sulfonylureas in Russia. 2016 Dec 8
19 25077812 Metabolism of agrochemicals and related environmental chemicals based on cytochrome P450s in mammals and plants. 2015 Jun 1
20 24464600 CYP2C9*2 allele increases risk for hypoglycemia in POR*1/*1 type 2 diabetic patients treated with sulfonylureas. 2014 Jan 5
21 24590592 Pharmacokinetics of tolbutamide and its metabolite 4-hydroxy tolbutamide in poloxamer 407-induced hyperlipidemic rats. 2014 Jul 1
22 23588782 Applications of CYP450 testing in the clinical setting. 2013 Jun 2
23 24324494 Pharmacogenetics of oral antidiabetic drugs. 2013 3
24 23153186 CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects. 2012 Dec 3
25 21142408 Sulfonylureas and on-clopidogrel platelet reactivity in type 2 diabetes mellitus patients. 2011 1
26 21213107 Impact of clinical factors and CYP2C9 variants for the risk of severe sulfonylurea-induced hypoglycemia. 2011 May 3
27 21356265 Reduced catalytic activity of human CYP2C9 natural alleles for gliclazide: molecular dynamics simulation and docking studies. 2011 Jun 1
28 21939641 Impact of genetic polymorphisms of cytochrome P450 2 C (CYP2C) enzymes on the drug metabolism and design of antidiabetics. 2011 Nov 15 1
29 19794412 Loss-of-function CYP2C9 variants improve therapeutic response to sulfonylureas in type 2 diabetes: a Go-DARTS study. 2010 Jan 4
30 20222813 Loss-of-function CYP2C9 variants: finding the correct clinical role for Type 2 diabetes pharmacogenetic testing. 2010 Mar 1
31 20698928 Potential CYP2C9-mediated drug-drug interactions in hospitalized type 2 diabetes mellitus patients treated with the sulphonylureas glibenclamide, glimepiride or glipizide. 2010 Oct 2
32 21121772 Effect of CYP2C9 polymorphisms on prescribed dose and time-to-stable dose of sulfonylureas in primary care patients with Type 2 diabetes mellitus. 2010 Nov 6
33 19891554 Presence of CYP2C9*3 allele increases risk for hypoglycemia in Type 2 diabetic patients treated with sulfonylureas. 2009 Nov 9
34 17597710 Cytochrome P450 2C9 *2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus. 2008 Feb 2
35 18503607 Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects. 2008 Jul 1
36 17963417 Pharmacogenetics of glucose-lowering drug treatment: a systematic review. 2007 1
37 15660356 Herbicide resistance in transgenic plants with mammalian P450 monooxygenase genes. 2005 Mar 1
38 15963101 Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents. 2005 Jul 2
39 16372821 Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. 2005 1
40 15349140 CYP2C9 genotype as a predictor of drug disposition in humans. 2004 Jul-Aug 1
41 12405866 Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection. 2002 2