Pub. Date : 2013
PMID : 24324494
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The gene variants in CYP2C9, ABCC8/KCNJ11, and TCF7L2 were associated with the effect of sulfonylureas. | Sulfonylurea Compounds | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | CYP2C9 encodes sulfonylurea metabolizing cytochrome P450 isoenzyme 2C9, ABCC8 and KCNJ11 genes encode proteins constituting ATP-sensitive K(+) channel which is a therapeutic target for sulfonylureas, and TCF7L2 is a gene with the strongest association with type 2 diabetes. | Sulfonylurea Compounds | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | CYP2C9 encodes sulfonylurea metabolizing cytochrome P450 isoenzyme 2C9, ABCC8 and KCNJ11 genes encode proteins constituting ATP-sensitive K(+) channel which is a therapeutic target for sulfonylureas, and TCF7L2 is a gene with the strongest association with type 2 diabetes. | Sulfonylurea Compounds | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |