| 1 |
34012401 | Novel Pan-Pim Kinase Inhibitors With Imidazopyridazine and Thiazolidinedione Structure Exert Potent Antitumor Activities. | 2021 |
2 |
| 2 |
34448628 | Phytoconstituents and Medicinal Plants for Anticancer Drug Discovery: Computational Identification of Potent Inhibitors of PIM1 Kinase. | 2021 Sep |
1 |
| 3 |
34770845 | Engineered Fully Human Single-Chain Monoclonal Antibodies to PIM2 Kinase. | 2021 Oct 25 |
2 |
| 4 |
32473133 | Resveratrol suppresses gastric cancer cell proliferation and survival through inhibition of PIM-1 kinase activity. | 2020 Aug 15 |
2 |
| 5 |
32479955 | A serine/threonine protein PIM kinase as a biomarker of cancer and a target for anti-tumor therapy. | 2020 Aug 15 |
2 |
| 6 |
33448694 | Virtual Screening and Design with Machine Intelligence Applied to Pim-1 Kinase Inhibitors. | 2020 Sep |
1 |
| 7 |
31072293 | New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations. | 2019 |
3 |
| 8 |
29384063 | Potential Pharmacological Inhibitors of Pim Kinase Under Clinical Trials. | 2018 |
2 |
| 9 |
29765150 | Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers. | 2018 May |
1 |
| 10 |
29042609 | Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors. | 2017 Oct 17 |
6 |
| 11 |
29057057 | From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome. | 2017 Oct 12 |
1 |
| 12 |
26824666 | Development and Application of a High-Throughput Fluorescence Polarization Assay to Target Pim Kinases. | 2016 Jan-Feb |
4 |
| 13 |
27285051 | Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors. | 2016 Jul 14 |
2 |
| 14 |
25582332 | Targeting Pim kinases for cancer treatment: opportunities and challenges. | 2015 |
4 |
| 15 |
26058458 | Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor. | 2015 Jul 6 |
1 |
| 16 |
26186558 | Targeting the Pim kinases in multiple myeloma. | 2015 Jul 17 |
1 |
| 17 |
26459208 | Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors. | 2015 Nov 15 |
2 |
| 18 |
24474669 | Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers. | 2014 Apr 1 |
2 |
| 19 |
24531473 | Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. | 2014 Feb |
2 |
| 20 |
24975213 | PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways. | 2014 Oct |
1 |
| 21 |
25050081 | Rhenium Complexes with Red-Light-Induced Anticancer Activity. | 2014 Feb 1 |
1 |
| 22 |
25087047 | Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition. | 2014 Sep 1 |
1 |
| 23 |
23436791 | A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors. | 2013 Mar |
4 |
| 24 |
23616352 | Selective bisubstrate inhibitors with sub-nanomolar affinity for protein kinase Pim-1. | 2013 Jun |
1 |
| 25 |
23623490 | Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design. | 2013 Jun 1 |
1 |
| 26 |
23755147 | Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure. | 2013 |
2 |
| 27 |
22272708 | The PIM kinases in hematological cancers. | 2012 Feb |
1 |
| 28 |
22306408 | A novel Pim-1 kinase inhibitor targeting residues that bind the substrate peptide. | 2012 Mar 30 |
1 |
| 29 |
22385334 | PIM1 kinase as a target for cancer therapy. | 2012 Apr |
1 |
| 30 |
22733119 | Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition. | 2012 Aug 21 |
2 |
| 31 |
23004574 | Insights from Pim1 structure for anti-cancer drug design. | 2012 Dec |
1 |
| 32 |
20808948 | Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements. | 2010 Aug 16 |
1 |
| 33 |
19723579 | Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases. | 2009 Nov |
1 |
| 34 |
19788246 | Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors. | 2009 Oct 22 |
1 |
| 35 |
15525646 | Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase. | 2005 Feb 18 |
1 |
| 36 |
15808862 | Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma. | 2005 Apr 22 |
1 |
| 37 |
16227208 | Structure and substrate specificity of the Pim-1 kinase. | 2005 Dec 16 |
1 |
| 38 |
9405361 | Autocatalytic processing of the ATP-dependent PIM1 protease: crucial function of a pro-region for sorting to mitochondria. | 1997 Dec 15 |
2 |
| 39 |
7957078 | Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria. | 1994 Nov 1 |
1 |