Title : Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.

Pub. Date : 2005 Apr 22

PMID : 15808862






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pim1 is unique among protein kinases due to the presence of a proline residue at position 123 that precludes the formation of the canonical second hydrogen bond between the hinge backbone and the adenine moiety of ATP. Adenosine Triphosphate Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens