272 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 25561870 | Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin. | 2014 Dec | 2 |
52 | 23064959 | Effect of abiraterone acetate plus prednisone on the pharmacokinetics of dextromethorphan and theophylline in patients with metastatic castration-resistant prostate cancer. | 2013 Jan | 2 |
53 | 23100173 | CYP2D6 phenotype indicative for optimized antiestrogen efficacy associates with outcome in early breast cancer patients. | 2013 Feb | 2 |
54 | 23340533 | Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain. | 2013 Jan | 3 |
55 | 23355638 | A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women. | 2013 Apr | 1 |
56 | 23665933 | CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes. | 2013 | 1 |
57 | 23835282 | Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6. | 2013 Sep | 3 |
58 | 23881421 | The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers. | 2013 Nov | 2 |
59 | 24013574 | A clinical investigation of inhibitory effect of panobinostat on CYP2D6 substrate in patients with advanced cancer. | 2013 Oct | 2 |
60 | 21842479 | Aloe vera juice: IC₅₀ and dual mechanistic inhibition of CYP3A4 and CYP2D6. | 2012 Mar | 1 |
61 | 21976621 | Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition. | 2012 Jan | 3 |
62 | 22039821 | Pharmacophore, QSAR, and binding mode studies of substrates of human cytochrome P450 2D6 (CYP2D6) using molecular docking and virtual mutations and an application to chinese herbal medicine screening. | 2012 Jul | 1 |
63 | 22277677 | Inter-individual variability of in vivo CYP2D6 activity in different genotypes. | 2012 | 1 |
64 | 22305191 | Polysaccharide peptides from Coriolus versicolor competitively inhibit model cytochrome P450 enzyme probe substrates metabolism in human liver microsomes. | 2012 Mar 15 | 1 |
65 | 22422635 | Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes. | 2012 Apr | 1 |
66 | 22451032 | Interleukin-6 and cytochrome-P450, reason for concern? | 2012 Sep | 1 |
67 | 22548589 | Serum dextromethorphan/dextrorphan metabolic ratio for CYP2D6 phenotyping in clinical practice. | 2012 Aug | 4 |
68 | 22553469 | The Discriminatory Value of CYP2D6 Genotyping in Predicting the Dextromethorphan/Dextrorphan Phenotype in Women with Breast Cancer. | 2012 Feb | 3 |
69 | 22762141 | Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection. | 2012 Aug | 1 |
70 | 22777153 | Endoxifen levels and its association with CYP2D6 genotype and phenotype: evaluation of a southern Brazilian population under tamoxifen pharmacotherapy. | 2012 Aug | 2 |
71 | 21228393 | Myoclonus after dextromethorphan administration in peritoneal dialysis. | 2011 Jan | 3 |
72 | 21365364 | In vitro determination of the effect of Andrographis paniculata extracts and andrographolide on human hepatic cytochrome P450 activities. | 2011 Jul | 1 |
73 | 21447389 | Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans. | 2011 Jun 14 | 1 |
74 | 21456632 | Sex differences in 3,4-methylenedioxymethamphetamine (MDMA; ecstasy)-induced cytochrome P450 2D6 inhibition in humans. | 2011 May | 1 |
75 | 21542294 | [CYP2D6*1, CYP2D6*10 co-expressed with CYPOR in Bac-to-Bac expression system and activity determination]. | 2011 Feb | 2 |
76 | 21542297 | [CYP2D6 genotypes and phenotypes in Chinese Han, Uygur and Kazakh populations]. | 2011 Feb | 1 |
77 | 21768449 | Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment. | 2011 Aug 20 | 2 |
78 | 21803659 | Cytochrome P450 2D6 phenotyping in an elderly population with dementia and response to galantamine in dementia: a pilot study. | 2011 Aug | 2 |
79 | 21849623 | Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys. | 2011 Nov | 2 |
80 | 22001938 | Heterologous expression of human cytochromes P450 2D6 and CYP3A4 in Escherichia coli and their functional characterization. | 2011 Dec | 1 |
81 | 24024018 | Metabolic capacity of CYP2D6 within an Iranian population (Mazandaran Province). | 2011 Spring | 2 |
82 | 20041473 | Effect of metabolic blockade on the psychoactive effects of dextromethorphan. | 2010 Jan | 4 |
83 | 20201775 | Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects. | 2010 Jan | 3 |
84 | 20473659 | Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations. | 2010 Sep | 3 |
85 | 20501912 | Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan. | 2010 Sep | 3 |
86 | 20700584 | Limited effects of frequent CYP2D6*36-*10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population. | 2010 Oct | 3 |
87 | 20881950 | Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan. | 2010 Nov | 3 |
88 | 20940534 | Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro. | 2010 Nov | 2 |
89 | 21386204 | Single time point diagnostic breath tests: a review. | 2010 Mar | 1 |
90 | 18543297 | Metabolism of dextrorphan by CYP2D6 in different recombinantly expressed systems and its implications for the in vitro assessment of dextromethorphan metabolism. | 2009 Feb | 4 |
91 | 18591960 | The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction. | 2009 Feb | 1 |
92 | 18838503 | Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymes. | 2009 Jan | 4 |
93 | 19059219 | The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol. | 2009 Mar 1 | 2 |
94 | 19133059 | Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment. | 2009 Jan | 2 |
95 | 19158312 | Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese. | 2009 Apr | 7 |
96 | 19356111 | O-demethylation of dextromethorphan using microbial cultures. | 2009 Jan | 2 |
97 | 19444798 | A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study. | 2009 Nov | 3 |
98 | 19817501 | Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I. | 2009 | 1 |
99 | 17899220 | Active-site structure, binding and redox activity of the heme-thiolate enzyme CYP2D6 immobilized on coated Ag electrodes: a surface-enhanced resonance Raman scattering study. | 2008 Jan | 1 |
100 | 17971818 | The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype. | 2008 Feb | 1 |