Title : The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers.

Pub. Date : 2013 Nov

PMID : 23881421






2 Functional Relationships(s)
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1 To determine the clinical effect of GSE on CYP2D6, the pharmacokinetic interaction between GSE and the sensitive CYP2D6 probe dextromethorphan in healthy adult volunteers was examined. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The results of this clinical study indicate that GSE appears to be safe to combine with drugs extensively metabolized by CYP2D6, such as dextromethorphan and tamoxifen. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens