| 1 |
34155225 | A comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab. | 2021 Jun 21 |
5 |
| 2 |
34187511 | Structural design of tetravalent T-cell engaging bispecific antibodies: improve developability by engineering disulfide bonds. | 2021 Jun 29 |
1 |
| 3 |
34211593 | Synthesis of Disulfide-Bridging Trehalose Polymers for Antibody and Fab Conjugation Using a Bis-Sulfone ATRP Initiator. | 2021 Mar 7 |
1 |
| 4 |
31971218 | Site-selective protein modification via disulfide rebridging for fast tetrazine/trans-cyclooctene bioconjugation. | 2020 Feb 14 |
2 |
| 5 |
32018094 | Bis(vinylsulfonyl)piperazines as efficient linkers for highly homogeneous antibody-drug conjugates. | 2020 Mar 15 |
2 |
| 6 |
33210532 | DiPODS: A Reagent for Site-Specific Bioconjugation via the Irreversible Rebridging of Disulfide Linkages. | 2020 Dec 16 |
1 |
| 7 |
30980702 | Characterization of Disulfide Bond Rebridged Fab-Drug Conjugates Prepared Using a Dual Maleimide Pyrrolobenzodiazepine Cytotoxic Payload. | 2019 Jun 18 |
3 |
| 8 |
33654871 | Conjugation of Fab' Fragments with Fluorescent Dyes for Single-Molecule Tracking On Live Cells. | 2019 Sep 20 |
3 |
| 9 |
29412660 | Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch. | 2018 Mar 6 |
1 |
| 10 |
29763554 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. | 2018 Jun 20 |
1 |
| 11 |
30121965 | Characterization of disulfide linkages at the hinge region of IgG antibodies by HPLC mass spectrometry. | 2018 Dec |
1 |
| 12 |
28216260 | Optimal expression of a Fab-effector fusion protein in Escherichia coli by removing the cysteine residues responsible for an interchain disulfide bond of a Fab molecule. | 2017 Apr |
4 |
| 13 |
29126850 | PSMA-targeted bispecific Fab conjugates that engage T cells. | 2017 Dec 15 |
2 |
| 14 |
27018805 | Elbow- and hinge-bending motions of IgG: Dielectric response and dynamic feature. | 2016 Sep |
1 |
| 15 |
27983990 | Selective disulfide reduction for labeling and enhancement of Fab antibody fragments. | 2016 Nov 25 |
2 |
| 16 |
25722499 | Design, Synthesis and Application of Fluorine-Labeled Taxoids as 19F NMR Probes for the Metabolic Stability Assessment of Tumor-Targeted Drug Delivery Systems. | 2015 Mar 1 |
1 |
| 17 |
25730439 | Conformational difference in human IgG2 disulfide isoforms revealed by hydrogen/deuterium exchange mass spectrometry. | 2015 Mar 17 |
1 |
| 18 |
24791606 | Bridging disulfides for stable and defined antibody drug conjugates. | 2014 Jun 18 |
1 |
| 19 |
25264323 | Protected hinge in the immunoglobulin G2-A2 disulfide isoform. | 2014 Dec |
1 |
| 20 |
23291144 | IgG2 disulfide isoform conversion kinetics. | 2013 Jun |
3 |
| 21 |
23929130 | Acid-cleavable thiomaleamic acid linker for homogeneous antibody-drug conjugation. | 2013 Sep 25 |
2 |
| 22 |
22723105 | PEGylation of antibody fragments for half-life extension. | 2012 |
2 |
| 23 |
22761163 | Relative stabilities of IgG1 and IgG4 Fab domains: influence of the light-heavy interchain disulfide bond architecture. | 2012 Sep |
3 |
| 24 |
21671135 | Disulfide scrambling in IgG2 monoclonal antibodies: insights from molecular dynamics simulations. | 2011 Dec |
1 |
| 25 |
20022943 | Enhanced formation of disulfide-bridged dimer (Fab-PE38)2 utilizing repeats of the Fab binding domain of protein G. | 2010 Feb 19 |
7 |
| 26 |
20039682 | Determination of Fab-hinge disulfide connectivity in structural isoforms of a recombinant human immunoglobulin G2 antibody. | 2010 Feb 1 |
1 |
| 27 |
20491447 | Ranking the susceptibility of disulfide bonds in human IgG1 antibodies by reduction, differential alkylation, and LC-MS analysis. | 2010 Jun 15 |
3 |
| 28 |
20616115 | PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1. | 2010 Sep |
1 |
| 29 |
19245794 | Higher cytotoxicity of divalent antibody-toxins than monovalent antibody-toxins. | 2009 Apr 24 |
1 |
| 30 |
19469538 | Amperometric immunosensor for detection of celiac disease toxic gliadin based on Fab fragments. | 2009 Jul 1 |
1 |
| 31 |
18055186 | Covalent immobilization of antibody fragments on well-defined polymer brushes via site-directed method. | 2008 Apr 1 |
1 |
| 32 |
18071941 | Engineering antibodies for stability and efficient folding. | 2008 |
1 |
| 33 |
18463717 | Screening of human antibody Fab fragment against HBsAg and the construction of its dsFv form. | 2008 Apr 24 |
1 |
| 34 |
18756111 | Disulfide bond bridged divalent antibody-toxin, (Fab-PE38fl)2, with the toxin PE38 fused to the light chain. | 2008 Aug |
1 |
| 35 |
17530757 | Direct immobilization of Fab' in nanocapillaries for manipulating mass-limited samples. | 2007 Jun 20 |
1 |
| 36 |
17688903 | Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein. | 2007 Nov 25 |
1 |
| 37 |
16995928 | Bifunctional recombinant fusion proteins for rapid detection of antibodies to both HIV-1 and HIV-2 in whole blood. | 2006 Sep 22 |
1 |
| 38 |
15769469 | Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability. | 2005 Apr 8 |
1 |
| 39 |
15345746 | A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis. | 2004 Dec |
1 |
| 40 |
15542644 | Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein. | 2004 Dec |
2 |
| 41 |
12488098 | Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display. | 2003 Jan 10 |
1 |
| 42 |
11739896 | Polyionic fusion peptides function as specific dimerization motifs. | 2001 Oct |
1 |
| 43 |
11804341 | A divalent recombinant immunotoxin formed by a disulfide bond between the extension peptide chains. | 2001 Dec 31 |
1 |
| 44 |
18432765 | Production of bispecific antibodies. | 2001 May |
1 |
| 45 |
11120833 | Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives. | 2000 Dec 15 |
2 |
| 46 |
10549572 | Stability and cytotoxicity of Fab-ricin A immunotoxins prepared with water soluble long chain heterobifunctional crosslinking agents. | 1999 Oct |
1 |
| 47 |
9769020 | Disulfide cross-linked Fab-aggregates: preparation and biodistribution. | 1998 |
1 |
| 48 |
8603822 | Improved tumor detection by anti-CEA chimeric Fab oligomers with disulfide linkages in a pancreatic-carcinoma-xenograft model. | 1996 Apr 10 |
1 |
| 49 |
7698350 | Domain interactions stabilize the alternatively folded state of an antibody Fab fragment. | 1995 Mar 27 |
1 |
| 50 |
7731044 | Association of antibody chains at different stages of folding: prolyl isomerization occurs after formation of quaternary structure. | 1995 Apr 21 |
1 |