Pub. Date : 2012 Sep
PMID : 22761163
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Relative stabilities of IgG1 and IgG4 Fab domains: influence of the light-heavy interchain disulfide bond architecture. | Disulfides | FA complementation group B | Homo sapiens |
| 2 | Introducing the IgG1 type L-H interchain disulfide bond (DSB) into the IgG4 Fab resulted in an increase in thermal stability to levels observed in the IgG1 Fab with the same variable region. | Disulfides | FA complementation group B | Homo sapiens |
| 3 | Introducing the IgG1 type L-H interchain disulfide bond (DSB) into the IgG4 Fab resulted in an increase in thermal stability to levels observed in the IgG1 Fab with the same variable region. | Disulfides | FA complementation group B | Homo sapiens |