Title : A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis.

Pub. Date : 2004 Dec

PMID : 15345746






1 Functional Relationships(s)
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1 A Fab fragment of anti-GHR(ext-mAb) inhibited GH-induced GHR disulfide linkage and signaling, as well as phorbol ester-induced GHR proteolysis, in a fashion similar to the intact antibody. Disulfides FA complementation group B Homo sapiens