Guanosine Diphosphate

RAP1A, member of RAS oncogene family ; Homo sapiens







30 Article(s)
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Pub. Year
#Total Relationships
1 35565390 TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells. 2022 Apr 30 1
2 29337043 Membrane-permeable Rab27A is a regulator of the acrosome reaction: Role of geranylgeranylation and guanine nucleotides. 2018 Apr 2
3 24704834 Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells. 2015 Mar 12 1
4 26634692 Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis. 2015 Dec 4 1
5 24470025 Pull-down assay for analysis of integrin-mediated activation of Rap proteins in adherent platelets. 2014 1
6 24349085 Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1. 2013 1
7 22614916 Rap1GAP alters leukemia cell differentiation, apoptosis and invasion in vitro. 2012 Aug 1
8 20124489 Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors. 2010 Feb 15 2
9 20170508 Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity. 2010 Feb 19 1
10 20413728 Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. 2010 Aug 1
11 20709748 Splice variants of SmgGDS control small GTPase prenylation and membrane localization. 2010 Nov 12 1
12 19332557 Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. 2009 Jun 1
13 17300802 Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach. 2007 Apr 6 1
14 12082090 MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases. 2002 Sep 6 1
15 10835426 CalDAG-GEFIII activation of Ras, R-ras, and Rap1. 2000 Aug 18 1
16 10985780 Mechanism of nucleotide release from Rho by the GDP dissociation stimulator protein. 2000 Sep 19 1
17 9882515 RAP1A GTP/GDP cycles determine the intracellular location of the late endocytic compartments and contribute to myogenic differentiation. 1999 Jan 10 2
18 10608844 RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans. 1999 Dec 31 2
19 9853756 Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. 1998 Dec 3 1
20 9266971 Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N). 1997 Aug 14 2
21 8832375 Oncogenic amino acid substitutions in the inhibitory rap-1A protein cause it to adopt a ras-p21-like conformation as computed using molecular dynamics. 1996 Jun 1
22 8838585 Prediction of the three-dimensional structure of the rap-1A protein from its homology to the ras-gene-encoded p21 protein. 1996 Jan 1
23 8900189 SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase. 1996 Oct 25 1
24 7833480 Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation. 1995 Feb 1 2
25 8034626 Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes. 1994 Jul 22 2
26 1763330 Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A. 1991 Dec 20 1
27 1773804 Genetic analysis of the K-rev-1 transformation-suppressor gene. 1991 Jun 1
28 1939245 Rap1A antagonizes the ability of Ras and Ras-Gap to inhibit muscarinic K+ channels. 1991 Nov 25 1
29 2110451 Guanine nucleotide binding properties of rap1 purified from human neutrophils. 1990 Apr 15 2
30 2160589 Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins. 1990 Jun 2