Title : RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans.

Pub. Date : 1999 Dec 31

PMID : 10608844






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hs-RA-GEF exhibited not only a GTP-dependent binding activity to Rap1A at its RA domain but also an activity to stimulate GDP/GTP exchange of Rap1A both in vitro and in vivo at the segment containing its REM and GEF domains. Guanosine Diphosphate RAP1A, member of RAS oncogene family Homo sapiens
2 On the other hand, Ce-RA-GEF associated with and stimulated GDP/GTP exchange of both Ras and Rap1A. Guanosine Diphosphate RAP1A, member of RAS oncogene family Homo sapiens