Title : TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells.

Pub. Date : 2022 Apr 30

PMID : 35565390






1 Functional Relationships(s)
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1 More precisely, TRPM8 inhibits cell migration and adhesion by trapping Rap1A in its GDP-bound inactive form, thus preventing its activation at the plasma membrane. Guanosine Diphosphate RAP1A, member of RAS oncogene family Homo sapiens