Benzo(a)pyrene

aryl hydrocarbon receptor ; Homo sapiens







148 Article(s)
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101 19559082 Aryl hydrocarbon receptor-dependent induction of the NADPH oxidase subunit NCF1/p47 phox expression leading to priming of human macrophage oxidative burst. 2009 Sep 15 9
102 19726680 Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione. 2009 Oct 23 1
103 19794518 Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells. 2009 Sep 1
104 18065724 Influence of TCDD and natural Ah receptor agonists on benzo[a]pyrene-DNA adduct formation in the Caco-2 human colon cell line. 2008 Jan 6
105 18289803 Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. 2008 Mar 15 6
106 18372000 Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene. 2008 Jul 15 6
107 18671994 Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway. 2008 Oct 15 1
108 18945501 Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo[a]pyrene (BaP). 2008 Nov 21 6
109 18989657 Synergism of aromatic amines and benzo[a]pyrene in induction of Ah receptor-dependent genes. 2008 Dec 1
110 19138996 Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation. 2008 Nov 1
111 17573710 Benzo[a]pyrene-dependent activation of transcription factors NF-kappaB and AP-1 related to tumor promotion in hepatoma cell cultures. 2007 May 1
112 17596880 Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. 2007 Jul 1
113 17682057 Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. 2007 Oct 3
114 17903170 Context-specific regulation of LINE-1. 2007 Oct 1
115 17944540 AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines. 2007 Dec 8
116 18001219 Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. 2007 1
117 16191477 Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand. 2006 Jan 4
118 16237193 Preferential induction of CYP1A1 and CYP1B1 in CCSP-positive cells. 2006 Jan 4
119 16480812 The aryl hydrocarbon receptor activates the retinoic acid receptoralpha through SMRT antagonism. 2006 Mar-Apr 2
120 16679317 Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene. 2006 Jul 21 2
121 16721748 Induction of the transferrin receptor gene by benzo[a]pyrene in breast cancer MCF-7 cells: potential as a biomarker of PAH exposure. 2006 Aug 1
122 16972788 Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells. 2006 Sep 1
123 15649379 Fast-track DRESSA: a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons. 2005 Feb 1 1
124 15681594 Constitutive activation and environmental chemical induction of the aryl hydrocarbon receptor/transcription factor in activated human B lymphocytes. 2005 May 2
125 15837074 Benzo[a]pyrene, but not 2,3,7,8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cells: a distinct signaling pathway. 2005 Apr 1
126 15860575 Human CD34-positive hematopoietic stem cells constitute targets for carcinogenic polycyclic aromatic hydrocarbons. 2005 Aug 4
127 15917307 Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. 2005 Oct 1
128 21783461 Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. 2005 Jan 2
129 14753257 A new luciferase reporter gene assay for the detection of androgenic and antiandrogenic effects based on a human prostate specific antigen promoter and PC3/AR human prostate cancer cells. 2004 Jan 2
130 15261788 Dioxin-like components in human breast milk collected from Hong Kong and Guangzhou. 2004 Sep 2
131 12566446 Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1. 2003 Apr 25 2
132 12594260 Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages. 2003 Mar 1 3
133 12799773 A role of aryl hydrocarbon receptor in the antiandrogenic effects of polycyclic aromatic hydrocarbons in LNCaP human prostate carcinoma cells. 2003 Jun 1
134 11141357 Benzo[g,h,i]perylene synergistically transactivates benzo[a]pyrene-induced CYP1A1 gene expression by aryl hydrocarbon receptor pathway. 2001 Jan 1 4
135 11764156 Aryl hydrocarbon receptor-mediated and estrogenic activities of oxygenated polycyclic aromatic hydrocarbons and azaarenes originally identified in extracts of river sediments. 2001 Dec 1
136 10605936 Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. 2000 Jan 1 1
137 10822009 Estrogen and aryl hydrocarbon receptor expression and crosstalk in human Ishikawa endometrial cancer cells. 2000 Apr 2
138 10230769 Divergent mechanisms for loss of Ah-responsiveness in benzo[a]pyrene- and adriamycinR-resistant MCF-7 cells. 1999 Jun 1 3
139 10496962 Resveratrol has antagonist activity on the aryl hydrocarbon receptor: implications for prevention of dioxin toxicity. 1999 Oct 2
140 9170146 Human Ah receptor (AHR) gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility. 1997 Apr 1
141 9407059 Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds. 1997 Dec 26 1
142 8921980 Relevance of different biological assays in assessing initiating and promoting properties of polycyclic aromatic hydrocarbons with respect to carcinogenic potency. 1996 Oct 28 1
143 8163517 Photoaffinity labeling of the Ah receptor with 3-[3H]methylcholanthrene and formation of a 165-kDa complex between the ligand-binding subunit and a novel cytosolic protein. 1994 Apr 22 1
144 8222045 CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. 1993 Oct 1
145 1654865 Detection and characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human colon adenocarcinoma cell line LS180. 1991 Oct 1
146 3040233 Ah receptor in human placenta: stabilization by molybdate and characterization of binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 3-methylcholanthrene, and benzo(a)pyrene. 1987 Sep 15 1
147 3011254 Ah receptor mediating induction of aryl hydrocarbon hydroxylase: detection in human lung by binding of 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin. 1986 Jul 1
148 2982617 Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase. 1985 Mar 1 1