Title : Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.

Pub. Date : 2005 Jan

PMID : 21783461






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BaP itself exhibited estrogenicity in the ER-CALUX assay due to bio-activation into estrogenic metabolites, probably via aryl hydrocarbon receptor (AhR) induced CYP activity. Benzo(a)pyrene aryl hydrocarbon receptor Homo sapiens
2 BaP itself exhibited estrogenicity in the ER-CALUX assay due to bio-activation into estrogenic metabolites, probably via aryl hydrocarbon receptor (AhR) induced CYP activity. Benzo(a)pyrene aryl hydrocarbon receptor Homo sapiens