Title : Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione.

Pub. Date : 2009 Oct 23

PMID : 19726680






1 Functional Relationships(s)
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1 The levels of hOGG1-dependent DNA strand breaks mediated by B[a]P-7,8-dione were lower in AhR-deficient Hepa and AhR knockdown H358 cells. Benzo(a)pyrene aryl hydrocarbon receptor Homo sapiens