Benzo(a)pyrene

aryl hydrocarbon receptor ; Homo sapiens







148 Article(s)
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51 25398514 Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism. 2016 Feb 2
52 26738610 Benzo[a]pyrene/aryl hydrocarbon receptor signaling inhibits osteoblastic differentiation and collagen synthesis of human periodontal ligament cells. 2016 Dec 1
53 26963242 Benzo(a)pyrene induces interleukin (IL)-6 production and reduces lipid synthesis in human SZ95 sebocytes via the aryl hydrocarbon receptor signaling pathway. 2016 Apr 3
54 27293999 The aryl hydrocarbon receptor agonist benzo(a)pyrene reactivates LINE-1 in HepG2 cells through canonical TGF-β1 signaling: implications in hepatocellular carcinogenesis. 2016 1
55 27486223 Divergent Ah Receptor Ligand Selectivity during Hominin Evolution. 2016 Oct 1
56 27544633 Aryl hydrocarbon receptor negatively regulates lipid synthesis and involves in cell differentiation of SZ95 sebocytes in vitro. 2016 Oct 25 6
57 27573671 An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells. 2016 Nov 1
58 27601158 Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc. 2016 Nov 1
59 24798859 Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. 2015 Oct 2
60 25224404 Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites. 2015 Dec 1
61 25781201 Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells. 2015 May 18 1
62 25896968 AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation. 2015 Jun 15 2
63 26041267 Neurotoxicity may be an overlooked consequence of benzo[a]pyrene exposure that is relevant to human health risk assessment. 2015 Apr-Jun 1
64 26350169 NcoA2-Dependent Inhibition of HIF-1α Activation Is Regulated via AhR. 2015 Dec 3
65 26561251 Aryl hydrocarbon receptor: Linking environment to immunity. 2015 Sep 2
66 23625689 The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines. 2014 Oct 2
67 24361490 Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene. 2014 Mar 5 4
68 24431215 Low-dose benzo(a)pyrene and its epoxide metabolite inhibit myogenic differentiation in human skeletal muscle-derived progenitor cells. 2014 Apr 4
69 24588654 Z-Ligustilide inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation. 2014 Apr 4
70 23228475 Cyprodinil as an activator of aryl hydrocarbon receptor. 2013 Feb 8 4
71 23439269 Association of aryl hydrocarbon receptor gene polymorphism with the neurobehavioral function and autonomic nervous system function changes induced by benzo[a]pyrene exposure in coke oven workers. 2013 Mar 3
72 23982178 Aryl hydrocarbon receptor and experimental autoimmune arthritis. 2013 Nov 1
73 21452393 Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells. 2012 Sep 2
74 21920623 ERα phenotype, estrogen level, and benzo[a]pyrene exposure modulate tumor growth and metabolism of lung adenocarcinoma cells. 2012 Mar 1
75 22155354 Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells. 2012 Feb 25 1
76 22561278 Identification of benzo[a]pyrene-induced cell cycle-associated alterations in MCF-7 cells using infrared spectroscopy with computational analysis. 2012 Aug 16 2
77 22581694 Alternation of extracellular matrix remodeling and apoptosis by activation of the aryl hydrocarbon receptor pathway in human periodontal ligament cells. 2012 Oct 3
78 22659362 Identification of the Ah-receptor structural determinants for ligand preferences. 2012 Sep 2
79 22837390 Vitamin D receptor activation enhances benzo[a]pyrene metabolism via CYP1A1 expression in macrophages. 2012 Nov 1
80 22951985 Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis. 2012 Sep 6 3
81 23036591 Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis. 2012 Oct 4 2
82 21256954 Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2. 2011 Apr 1
83 21292640 Aryl hydrocarbon receptor ligands of widely different toxic equivalency factors induce similar histone marks in target gene chromatin. 2011 May 4
84 21316925 An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway. 2011 Apr 1
85 21453744 T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not aryl hydrocarbon receptor-dependent interleukin-8 secretion in the human intestinal epithelial cell line Caco-2. 2011 Jun 18 1
86 21720915 Interaction of a functionalized complex of the flavonoid hesperetin with the AhR pathway and CYP1A1 expression: involvement in its protective effects against benzo[a]pyrene-induced oxidative stress in human skin. 2011 Oct 1
87 21802500 Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands. 2011 Oct 10 2
88 21911031 Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcαRI by the environmental contaminant benzo(a)pyrene in human macrophages. 2011 Nov 28 3
89 19828881 Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. 2010 Jan 1
90 20228066 Diminished carcinogen detoxification is a novel mechanism for hypoxia-inducible factor 1-mediated genetic instability. 2010 May 7 1
91 20307623 Exposure of human skin to benzo[a]pyrene: role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation. 2010 May 27 5
92 20334656 Disruption of human plasma cell differentiation by an environmental polycyclic aromatic hydrocarbon: a mechanistic immunotoxicological study. 2010 Mar 24 2
93 20371965 Malondialdehyde-modified low density lipoprotein (MDA-LDL)-induced cell growth was suppressed by polycyclic aromatic hydrocarbons (PAHs). 2010 Apr 5
94 20553787 Inhibitory effects of chrysoeriol on DNA adduct formation with benzo[a]pyrene in MCF-7 breast cancer cells. 2010 Jul-Aug 3
95 20868228 Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products. 2010 Nov 3
96 19131362 NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons. 2009 May 1 1
97 19244278 The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. 2009 May 6
98 19302817 TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a). 2009 Mar 27 2
99 19358281 Aryl hydrocarbon receptor activation and overexpression upregulated fibroblast growth factor-9 in human lung adenocarcinomas. 2009 Aug 15 5
100 19486938 Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene. 2009 Sep 2