Guanosine Triphosphate

ADP ribosylation factor 6 ; Homo sapiens







82 Article(s)
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1 33443153 In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1. 2021 Jan 5 1
2 32119711 Angiotensin II promotes podocyte injury by activating Arf6-Erk1/2-Nox4 signaling pathway. 2020 2
3 32473257 The Vps52 subunit of the GARP and EARP complexes is a novel Arf6-interacting protein that negatively regulates neurite outgrowth of hippocampal neurons. 2020 Oct 15 3
4 30735346 Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases. 2019 Mar 15 1
5 31040262 CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. 2019 Apr 30 2
6 31692781 CD13 regulation of membrane recycling: implications for cancer dissemination. 2019 2
7 27776975 Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs. 2017 Jan 2
8 29348842 DDEFL1 correlated with Rho GTPases activity in breast cancer. 2017 Dec 22 2
9 25713146 ADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation. 2015 Apr 10 2
10 25793724 A mutational analysis of residues in cholera toxin A1 necessary for interaction with its substrate, the stimulatory G protein Gsα. 2015 Mar 18 1
11 26185744 Increased expression of ARF GTPases in prostate cancer tissue. 2015 1
12 26229970 Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages. 2015 2
13 26498519 RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes. 2015 Nov 27 1
14 24526684 ADP ribosylation factor 6 (Arf6) acts through FilGAP protein to down-regulate Rac protein and regulates plasma membrane blebbing. 2014 Apr 4 1
15 24581425 Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6. 2014 May 2
16 25296758 Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6). 2014 Nov 28 3
17 25450674 Cytohesin 2/ARF6 regulates preadipocyte migration through the activation of ERK1/2. 2014 Dec 15 2
18 22998223 Arf6 regulation of Gyrating-clathrin. 2013 Jan 1
19 23295182 ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology. 2013 Feb 22 2
20 22226746 An ARF6/Rab35 GTPase cascade for endocytic recycling and successful cytokinesis. 2012 Jan 24 1
21 22666423 ADP-ribosylation factor 6 expression and activation are reduced in myometrium in complicated pregnancies. 2012 3
22 22916275 ARF6-dependent regulation of P2Y receptor traffic and function in human platelets. 2012 2
23 21346189 HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes. 2011 Apr 15 3
24 21439824 Decoupling of activation and effector binding underlies ARF6 priming of fast endocytic recycling. 2011 Apr 12 3
25 22045739 Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcγR-mediated phagocytosis. 2011 Nov 1 1
26 20462959 Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis. 2010 Jul 1 1
27 20709080 SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6. 2010 Oct 1 1
28 20713492 Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6. 2010 Oct 1
29 21686261 Subtle functional defects in the Arf-specific guanine nucleotide exchange factor IQSEC2 cause non-syndromic X-linked intellectual disability. 2010 Sep 1
30 19211056 ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. 2009 Feb 10 1
31 19365558 ARF6-mediated endosome recycling reverses lipid accumulation defects in Niemann-Pick Type C disease. 2009 3
32 19626334 Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway. 2009 Sep 1
33 19644450 The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4. 2009 Sep 16 1
34 19686593 Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6. 2009 Aug 17 2
35 19896381 ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles. 2009 Dec 1 2
36 19948141 Metastasis: wherefore arf thou? 2009 Dec 1 1
37 18094045 Fbx8 makes Arf6 refractory to function via ubiquitination. 2008 Mar 1
38 18326492 Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. 2008 May 2 2
39 18597672 Arf family GTP loading is activated by, and generates, positive membrane curvature. 2008 Sep 1 1
40 17409355 Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains. 2007 Jun 1
41 17719203 ARF6 regulates angiotensin II type 1 receptor endocytosis by controlling the recruitment of AP-2 and clathrin. 2007 Nov 2
42 17786213 Identification of a guanine nucleotide exchange factor for Arf3, the yeast orthologue of mammalian Arf6. 2007 Sep 5 1
43 17804820 ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling. 2007 Nov 1
44 16636290 Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. 2006 May 2 2
45 16737952 Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4. 2006 Aug 10
46 16805823 Involvement of a novel ADP-ribosylation factor GTPase-activating protein, SMAP, in membrane trafficking: implications in cancer cell biology. 2006 Sep 2
47 17077126 ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. 2006 Nov 15 2
48 15642342 Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins. 2005 Jan 17 1
49 15802264 The small G-protein Arf6GTP recruits the AP-2 adaptor complex to membranes. 2005 Jun 3 5
50 15897187 ARF6 GTPase controls bacterial invasion by actin remodelling. 2005 May 15 1