Title : Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6.

Pub. Date : 2014 May

PMID : 24581425






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 As shown by western blotting, ARF6 interacted with cytohesin-2 and was present in an active GTP-bound form under basal conditions. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens
2 CONCLUSIONS: Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 in a GTP-bound state. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens