Title : Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages.

Pub. Date : 2015

PMID : 26229970






2 Functional Relationships(s)
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1 Moreover, the simultaneous expression of ACAP2-a Rab35 effector protein-with GTP-locked Rab35 or the expression of plasma membrane-targeted ACAP2 showed a marked inhibitory effect on phagocytosis through ARF6 inactivation by the GAP activity of ACAP2. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens
2 Furthermore, the expression of GDP- or GTP-locked ARF6 mutants also suppresses the uptake of zymosan. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens