Title : CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration.

Pub. Date : 2019 Apr 30

PMID : 31040262






2 Functional Relationships(s)
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1 In migrating cells, a complex containing phosphorylated CD13, IQGAP1, GTP-bound (active) ARF6, and EFA6 at the leading edge promoted the ARF6 GTPase cycling and cell migration. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens
2 In migrating cells, a complex containing phosphorylated CD13, IQGAP1, GTP-bound (active) ARF6, and EFA6 at the leading edge promoted the ARF6 GTPase cycling and cell migration. Guanosine Triphosphate ADP ribosylation factor 6 Homo sapiens