Verapamil

ATP-binding cassette, subfamily B (MDR/TAP), member 1B ; Rattus norvegicus







160 Article(s)
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1 34496661 Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice? 2022 Jan 1
2 34798162 Intestinal metabolism and absorption mechanism of multi-components in Gaultheria leucocarpa var. yunnanensis - An assessment using in situ and in vitro models, comparing gut segments in pathological with physiological conditions. 2022 Mar 25 3
3 34971693 PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats. 2022 Feb 1
4 35566380 Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from Isolona hexaloba on Rhodamine Efflux by Abcb1b from Rat Glycocholic-Acid-Resistant Hepatocarcinoma Cells. 2022 May 9 2
5 33793796 Possible roles of intestinal P-glycoprotein and cytochrome P450 3A on the limited oral absorption of irinotecan. 2021 Mar 4 3
6 33965372 Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain "gatekeeper" function. 2021 Jul 15 2
7 31863502 Short-chain fatty acids oppositely altered expressions and functions of intestinal cytochrome P4503A and P-glycoprotein and affected pharmacokinetics of verapamil following oral administration to rats. 2020 Mar 1
8 32078103 Evaluation of the Role of P-glycoprotein (P-gp)-Mediated Efflux in the Intestinal Absorption of Common Substrates with Elacridar, a P-gp Inhibitor, in Rats. 2020 Jun 2
9 32134711 Quantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G. 2020 Apr 1 2
10 33389978 In Situ Absorption Study of Acebutolol by Modulating P-glycoprotein with Verapamil in Rats. 2020 Dec 23 2
11 29556829 Evaluation of Intestinal Absorption and Bioavailability of a Bergenin-Phospholipid Complex Solid Dispersion in Rats. 2018 May 1
12 29751140 Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy. 2018 Aug 25 1
13 27193034 PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression. 2017 Apr 1
14 27747446 The effects of 18β-glycyrrhetinic acid and glycyrrhizin on intestinal absorption of paeoniflorin using the everted rat gut sac model. 2017 Jan 1
15 27925244 The absorption enhancement of norisoboldine in the duodenum of adjuvant-induced arthritis rats involves the impairment of P-glycoprotein. 2017 Jan 3
16 28223141 Activation of melatonin receptor (MT1/2) promotes P-gp transporter in methamphetamine-induced toxicity on primary rat brain microvascular endothelial cells. 2017 Jun 1
17 28367925 Selective Absorption of Dietary Sphingoid Bases from the Intestine via Efflux by P-Glycoprotein in Rats. 2017 1
18 28463810 Rational design of hybrid nanomicelles integrating mucosal penetration and P-glycoprotein inhibition for efficient oral delivery of paclitaxel. 2017 Jul 1 1
19 28650628 Synthesis and Evaluation of New Fluorine-18 Labeled Verapamil Analogs To Investigate the Function of P-Glycoprotein in the Blood-Brain Barrier. 2017 Sep 20 1
20 28755970 Differences of first-pass effect in the liver and intestine contribute to the stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats. 2017 Sep 14 1
21 26031900 Hepatic, gastric and intestinal first-pass effects of vitexin-2''-O-rhamnoside in rats by ultra-high-performance liquid chromatography. 2016 Feb 1
22 26446867 Possible role of P-glycoprotein in the neuroprotective mechanism of berberine in intracerebroventricular streptozotocin-induced cognitive dysfunction. 2016 Jan 2
23 26554626 Effect of Subchronic Intravenous Morphine Infusion and Naloxone-Precipitated Morphine Withdrawal on P-gp and Bcrp at the Rat Blood-Brain Barrier. 2016 Jan 1
24 26711120 Absorption characteristic of paeoniflorin-6'-O-benzene sulfonate (CP-25) in in situ single-pass intestinal perfusion in rats. 2016 Sep 3
25 26797108 Blockade of P-Glycoprotein Decreased the Disposition of Phenformin and Increased Plasma Lactate Level. 2016 Mar 1 2
26 26932816 The Consequence of Drug-Drug Interactions Influencing the Interplay between P-Glycoprotein and Cytochrome P450 3a: An Ex Vivo Study with Rat Precision-Cut Intestinal Slices. 2016 May 1
27 27604118 Increased Intestinal Absorption of Genistein by Coadministering Verapamil in Rats. 2016 Oct 2
28 26102179 Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration. 2015 Sep 2
29 26460146 Increased intestinal P-glycoprotein expression and activity with progression of diabetes and its modulation by epigallocatechin-3-gallate: Evidence from pharmacokinetic studies. 2015 Nov 15 2
30 24189249 Investigation of the functional role of P-glycoprotein in limiting the oral bioavailability of lumefantrine. 2014 4
31 24378368 P‑glycoprotein inhibition increases the transport of dauricine across the blood‑brain barrier. 2014 Mar 2
32 24555505 Hepatic, gastric, and intestinal first-pass effects of vitexin in rats. 2014 Aug 1
33 24729214 Impact of hypoxia-related tumor acidosis on cytotoxicity of different chemotherapeutic drugs in vitro and in vivo. 2014 1
34 24786847 Effects of piperine on the intestinal permeability and pharmacokinetics of linarin in rats. 2014 Apr 30 1
35 24948812 Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers. 2014 Jun 18 1
36 24985475 Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats. 2014 Jul 1 4
37 25625052 Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma. 2014 Nov 2
38 23142723 Penetration of verapamil across blood brain barrier following cerebral ischemia depending on both paracellular pathway and P-glycoprotein transportation. 2013 Jan 4
39 23383092 In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties. 2013 2
40 23620249 Evaluation of rat in vivo fetal-to-maternal transfer clearances of various xenobiotics by umbilical perfusion. 2013 Sep 2
41 23630447 Genomic profiling reveals the potential role of TCL1A and MDR1 deficiency in chemotherapy-induced cardiotoxicity. 2013 1
42 23852717 In vitro investigation of amyloid-β hepatobiliary disposition in sandwich-cultured primary rat hepatocytes. 2013 Oct 2
43 24028617 Hepatic and gastrointestinal first-pass effects of vitexin-4″-O-glucoside in rats. 2013 Oct 2
44 24044638 Effect of P-glycoprotein on the rat intestinal permeability and metabolism of the BDDCS class 1 drug verapamil. 2013 Nov 4 4
45 24250670 Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS. 2013 Winter 2
46 24348021 P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy. 2013 1
47 24490575 [Study on intestinal absorption of formononetin in Millettia nitita var. hirsutissima in rats]. 2013 Oct 1
48 22250926 Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats. 2012 Jun 1
49 23072492 Pharmacokinetic modeling of P-glycoprotein function at the rat and human blood-brain barriers studied with (R)-[11C]verapamil positron emission tomography. 2012 Oct 16 1
50 20579678 Teratogenic and cytogenetic effects of ivermectin and its interaction with P-glycoprotein inhibitor. 2011 Feb 1