Title : Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from Isolona hexaloba on Rhodamine Efflux by Abcb1b from Rat Glycocholic-Acid-Resistant Hepatocarcinoma Cells.

Pub. Date : 2022 May 9

PMID : 35566380






2 Functional Relationships(s)
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1 Compared to verapamil, a widely used inhibitor of P-gp, curine and guattegaumerine were found to be weak inhibitors of MDR1/P-Glycoprotein. Verapamil ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
2 Compared to verapamil, a widely used inhibitor of P-gp, curine and guattegaumerine were found to be weak inhibitors of MDR1/P-Glycoprotein. Verapamil ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus