Pub. Date : 2013 Oct
PMID : 24028617
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For the study on regulatory mechanisms of cytochrome P450 3A (CYP3A) and P-glycoprotein (P-gp) on the bioavailability of VOG, the solution of verapamil hydrochloride (60 mg/kg) was instilled into intestine at 10 min before the infusion of VOG. | Verapamil | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |
| 2 | The value of AUC0 for verapamil group was approximately 1.4-fold higher than that for normal saline group, meaning that perhaps CYP3A participated in the metabolism of VOG or P-gp transported VOG outside. | Verapamil | ATP-binding cassette, subfamily B (MDR/TAP), member 1B | Rattus norvegicus |