| 1 |
33514677 | Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARα-Dependent Astrocytic GDNF Pathway. | 2021 Mar 10 |
4 |
| 2 |
30898012 | Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model. | 2020 Jan |
4 |
| 3 |
30680004 | Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPARα and SREBP1. | 2019 Feb |
3 |
| 4 |
29534628 | Gemfibrozil has antidepressant effects in mice: Involvement of the hippocampal brain-derived neurotrophic factor system. | 2018 Apr |
1 |
| 5 |
29662003 | PPAR Agonists and Metabolic Syndrome: An Established Role? | 2018 Apr 14 |
1 |
| 6 |
30260990 | Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers. | 2018 |
2 |
| 7 |
28343425 | PPAR-α agonists are still on the rise: an update on clinical and experimental findings. | 2017 May |
1 |
| 8 |
28752027 | The potential of natural products for targeting PPARα. | 2017 Jul |
1 |
| 9 |
25750174 | Activation of peroxisome proliferator-activated receptor α induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. | 2015 Apr 17 |
2 |
| 10 |
24180432 | Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study. | 2014 Jan |
1 |
| 11 |
25147562 | PPARα: A Master Regulator of Bilirubin Homeostasis. | 2014 |
1 |
| 12 |
22879602 | Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β. | 2012 Oct 5 |
2 |
| 13 |
21889235 | Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism. | 2011 Oct |
2 |
| 14 |
21966330 | Medicinal Chemistry and Actions of Dual and Pan PPAR Modulators. | 2011 |
1 |
| 15 |
19779008 | Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza. | 2010 Dec |
1 |
| 16 |
20953357 | Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism. | 2010 |
3 |
| 17 |
19376321 | Efficacy of gemfibrozil in the primary prevention of atrial fibrillation in a large randomized controlled trial. | 2009 May |
1 |
| 18 |
18092840 | Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases. | 2008 |
1 |
| 19 |
18420459 | Confronting an influenza pandemic with inexpensive generic agents: can it be done? | 2008 Sep |
1 |
| 20 |
18678301 | Efficacy and safety of a potent and selective peroxisome proliferator activated receptor alpha agonist in subjects with dyslipidemia and type 2 diabetes mellitus. | 2008 Aug 15 |
2 |
| 21 |
18799592 | Novel peroxisome proliferator-activated receptor alpha agonists lower low-density lipoprotein and triglycerides, raise high-density lipoprotein, and synergistically increase cholesterol excretion with a liver X receptor agonist. | 2008 Dec |
1 |
| 22 |
17897018 | PPARs and diabetes-associated atherosclerosis. | 2007 |
2 |
| 23 |
16221474 | The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT). | 2006 Jul |
1 |
| 24 |
16782410 | Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications. | 2006 Jul |
1 |
| 25 |
16828346 | Managing diabetic dyslipidaemia--beyond LDL-C:HDL-C and triglycerides. | 2006 Aug |
1 |
| 26 |
15618549 | Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation. | 2005 Mar |
1 |
| 27 |
16101410 | PPARs as targets for metabolic and cardiovascular diseases. | 2005 Aug |
1 |
| 28 |
16226225 | Fibrates inhibit aldose reductase activity in the forward and reverse reactions. | 2005 Nov 25 |
2 |
| 29 |
15100326 | Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease. | 2004 May 1 |
2 |
| 30 |
15142970 | Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. | 2004 May 14 |
1 |
| 31 |
15194003 | PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells. | 2004 Jul 15 |
1 |
| 32 |
12746275 | Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. | 2003 Jun |
1 |
| 33 |
11914252 | Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease. | 2002 Mar 26 |
1 |
| 34 |
12172398 | Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil. | 2002 Jul-Aug |
5 |
| 35 |
12244038 | Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. | 2002 Nov 29 |
3 |
| 36 |
11474570 | [New concepts on the mechanism of action of fibrates and therapeutic prospectives in atherosclerosis]. | 2001 |
1 |
| 37 |
11712864 | PPARS, metabolic disease and atherosclerosis. | 2001 Nov |
1 |
| 38 |
10494028 | Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells. | 1999 |
1 |
| 39 |
9484993 | RXR agonists activate PPARalpha-inducible genes, lower triglycerides, and raise HDL levels in vivo. | 1998 Feb |
2 |