Title : Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil.

Pub. Date : 2002 Jul-Aug

PMID : 12172398






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1 Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil. Gemfibrozil peroxisome proliferator activated receptor alpha Homo sapiens
2 PURPOSE: The effect of gemfibrozil is mediated by the activation of peroxisome proliferator-activated receptor alpha (PPAR alpha). Gemfibrozil peroxisome proliferator activated receptor alpha Homo sapiens
3 PURPOSE: The effect of gemfibrozil is mediated by the activation of peroxisome proliferator-activated receptor alpha (PPAR alpha). Gemfibrozil peroxisome proliferator activated receptor alpha Homo sapiens
4 The objective of this study was to determine whether the lipid response to gemfibrozil therapy is influenced by the PPAR alpha-L162V polymorphism. Gemfibrozil peroxisome proliferator activated receptor alpha Homo sapiens
5 CONCLUSION: These results suggest that the HDL(2)-C response to gemfibrozil is modulated by the PPAR alpha-L162V polymorphism. Gemfibrozil peroxisome proliferator activated receptor alpha Homo sapiens