Pub. Date : 2010
PMID : 20953357
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These events are causally related to hepatotoxicity and hepatocarcinogenicity of gemfibrozil in rodents via peroxisome proliferator activated receptor-alpha (PPARalpha) activation; however, there is widespread evidence that activation of PPARalpha in humans results in expression of genes involved in lipid metabolism, but not in hepatocellular proliferation. | Gemfibrozil | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 2 | These events are causally related to hepatotoxicity and hepatocarcinogenicity of gemfibrozil in rodents via peroxisome proliferator activated receptor-alpha (PPARalpha) activation; however, there is widespread evidence that activation of PPARalpha in humans results in expression of genes involved in lipid metabolism, but not in hepatocellular proliferation. | Gemfibrozil | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 3 | These events are causally related to hepatotoxicity and hepatocarcinogenicity of gemfibrozil in rodents via peroxisome proliferator activated receptor-alpha (PPARalpha) activation; however, there is widespread evidence that activation of PPARalpha in humans results in expression of genes involved in lipid metabolism, but not in hepatocellular proliferation. | Gemfibrozil | peroxisome proliferator activated receptor alpha | Homo sapiens |