Serine

signal transducer and activator of transcription 3 ; Homo sapiens







226 Article(s)
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1 34626364 Activation of STAT3 signaling pathway in the kidney of COVID-19 patients. 2022 Apr 1
2 34857889 Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer. 2022 Feb 2
3 33098871 Phosphorylation of STAT3 by axonal Cdk5 promotes axonal regeneration by modulating mitochondrial activity. 2021 Jan 2
4 33639070 SHP1 Decreases Level of P-STAT3 (Ser727) and Inhibits Proliferation and Migration of Pancreatic Cancer Cells. 2021 2
5 33772065 Nuclear and cytosolic pS727-STAT3 levels correlate with overall survival of patients affected by clear cell renal cell carcinoma (ccRCC). 2021 Mar 26 2
6 33972660 FMRP regulates STAT3 mRNA localization to cellular protrusions and local translation to promote hepatocellular carcinoma metastasis. 2021 May 10 1
7 34100606 Chrysin Inhibits Pseudo-allergic Reaction by Suppressing Mitochondrial STAT3 Activation via MAS-Related GPR Family Member X2. 2021 Jun 16 1
8 34440160 The Roles of Post-Translational Modifications in STAT3 Biological Activities and Functions. 2021 Aug 4 1
9 34699606 Zinc induces reactive astrogliosis through ERK-dependent activation of Stat3 and promotes synaptic degeneration. 2021 Dec 4
10 34731785 STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications. 2021 Dec 1
11 34884773 Opposing Effects of Chelidonine on Tyrosine and Serine Phosphorylation of STAT3 in Human Uveal Melanoma Cells. 2021 Nov 30 3
12 34885140 Mitochondrial Plasticity Promotes Resistance to Sorafenib and Vulnerability to STAT3 Inhibition in Human Hepatocellular Carcinoma. 2021 Nov 30 1
13 32114280 Curcumin mediates attenuation of pro-inflammatory interferon γ and interleukin 17 cytokine responses in psoriatic disease, strengthening its role as a dietary immunosuppressant. 2020 Mar 1
14 32192776 NME4 modulates PD-L1 expression via the STAT3 signaling pathway in squamous cell carcinoma. 2020 May 21 1
15 32201262 Constitutive STAT3 Serine Phosphorylation Promotes Helicobacter-Mediated Gastric Disease. 2020 Jun 3
16 32681941 6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway. 2020 Sep 15 2
17 32803097 Adrenal Corticomedullary Mixed Tumor Associated With the FGFR4-G388R Variant. 2020 Sep 1 2
18 33003453 Perspectives Regarding the Intersections between STAT3 and Oxidative Metabolism in Cancer. 2020 Sep 29 1
19 33313091 Stromal cells promote chemoresistance of acute myeloid leukemia cells via activation of the IL-6/STAT3/OXPHOS axis. 2020 Nov 2
20 30466966 The role of STAT3 protein as a prognostic factor in the clear cell renal carcinoma. Systematic review. 2019 Apr 1
21 30776726 Cytokines use different intracellular mechanisms to upregulate the membrane expression of CX3CR1 in human monocytes. 2019 Apr 1
22 30920934 S27 of IFNα1 Contributes to Its Low Affinity for IFNAR2 and Weak Antiviral Activity. 2019 May 1
23 31398350 p66Shc promotes HCC progression in the tumor microenvironment via STAT3 signaling. 2019 Oct 15 1
24 31451482 TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma. 2019 Oct 1
25 31481496 Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity. 2019 Oct 15 2
26 29431732 STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. 2018 Mar 1 2
27 29488000 Bilateral activation of STAT3 by phosphorylation at the tyrosine-705 (Y705) and serine-727 (S727) positions and its nuclear translocation in primary sensory neurons following unilateral sciatic nerve injury. 2018 Jul 2
28 29652915 Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes. 2018 2
29 29683208 A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras. 2018 Sep 1
30 29774125 The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma. 2018 Apr 24 1
31 30208623 Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling. 2018 Sep 11 1
32 30263097 STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells. 2018 Sep 14 1
33 30323145 Downregulation of signal transduction and STAT3 expression exacerbates oxidative stress mediated by NLRP3 inflammasome. 2018 Dec 1
34 30428347 Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation. 2018 Nov 13 1
35 26705936 Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals. 2017 Jan 1
36 27966451 FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors. 2017 Jan 10 2
37 28130399 Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex. 2017 May 5
38 28188289 Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis. 2017 Mar 24 1
39 28188292 Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. 2017 Mar 31 1
40 28542650 Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion. 2017 2
41 28781685 Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells. 2017 Aug 1
42 28968425 Gene expression profiling of hepatocarcinogenesis in a mouse model of chronic hepatitis B. 2017 2
43 29212252 C-C motif chemokine receptor 1 (CCR1) is a target of the EGF-AKT-mTOR-STAT3 signaling axis in breast cancer cells. 2017 Nov 7 1
44 25736961 STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma. 2016 Jan 2
45 26727576 A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture. 2016 Jan 4 1
46 26783739 STAT3-Ser/Hes3 Signaling: A New Molecular Component of the Neuroendocrine System? 2016 Feb 2
47 27064016 Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells. 2016 May 15 1
48 27502766 Mitochondrial STAT3 is negatively regulated by SOCS3 and upregulated after spinal cord injury. 2016 Oct 5
49 25512602 Adenosine 5'-monophosphate-activated protein kinase regulates IL-10-mediated anti-inflammatory signaling pathways in macrophages. 2015 Jan 15 1
50 25584415 Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation. 2015 Mar 7