Serine

signal transducer and activator of transcription 3 ; Homo sapiens







226 Article(s)
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51 26045618 Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion. 2015 Aug 1 1
52 26106584 STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance. 2015 1
53 26138072 A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. 2015 Sep 1
54 26330924 Prognostic Significance of Serine-Phosphorylated STAT3 Expression in pT1-T2 Oral Tongue Carcinoma. 2015 Sep 2
55 27127727 Mitochondrial STAT3 and reactive oxygen species: A fulcrum of adipogenesis? 2015 2
56 23455323 Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor. 2014 Feb 27 2
57 23913134 Histone deacetylase 3 as a novel therapeutic target in multiple myeloma. 2014 Mar 2
58 24389215 The STAT3-Ser/Hes3 signaling axis in cancer. 2014 Jan 1 1
59 24396070 SH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiation. 2014 Mar 2
60 24487064 A non-canonical function of eukaryotic elongation factor 1A1: regulation of interleukin-6 expression. 2014 May 1
61 24582688 Reactive oxygen species contribute to arsenic-induced EZH2 phosphorylation in human bronchial epithelial cells and lung cancer cells. 2014 May 1 1
62 24615012 Signal integration and gene induction by a functionally distinct STAT3 phosphoform. 2014 May 2
63 24625004 FGFR4 polymorphic variants modulate phenotypic features of Cushing disease. 2014 Apr 1
64 24726840 Reduced phosphorylation of Stat3 at Ser-727 mediated by casein kinase 2 - protein phosphatase 2A enhances Stat3 Tyr-705 induced tumorigenic potential of glioma cells. 2014 Aug 9
65 24847057 Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes. 2014 Jun 27 1
66 25031733 STAT3 serine 727 phosphorylation influences clinical outcome in glioblastoma. 2014 1
67 25038288 Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor. 2014 Oct 1
68 25074934 Cell surface epidermal growth factor receptors increase Src and c-Cbl activity and receptor ubiquitylation. 2014 Sep 12 1
69 25089666 STAT3 Activities and Energy Metabolism: Dangerous Liaisons. 2014 Jul 31 2
70 25219839 Effect of angiotensin II on STAT3 mediated atrial structural remodeling. 2014 Aug 1
71 25299776 Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727. 2014 Oct 9 3
72 25383546 The synthetic tryptanthrin analogue suppresses STAT3 signaling and induces caspase dependent apoptosis via ERK up regulation in human leukemia HL-60 cells. 2014 2
73 23174178 Activation of JAK-STAT3 signaling pathway in chronic subdural hematoma outer membranes. 2013 Feb 8 1
74 23329839 Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway. 2013 Mar 1 4
75 23740979 Kaposi's sarcoma-associated herpesvirus kaposin B induces unique monophosphorylation of STAT3 at serine 727 and MK2-mediated inactivation of the STAT3 transcriptional repressor TRIM28. 2013 Aug 1
76 23831387 STAT3 integrates cytokine and neurotrophin signals to promote sympathetic axon regeneration. 2013 Sep 1
77 23872421 GDNF family ligand dependent STAT3 activation is mediated by specific alternatively spliced isoforms of GFRα2 and RET. 2013 Dec 1
78 24055291 Quinazolino linked 4β-amidopodophyllotoxin conjugates regulate angiogenic pathway and control breast cancer cell proliferation. 2013 Nov 1 1
79 24101906 The STAT3-Ser/Hes3 signaling axis: an emerging regulator of endogenous regeneration and cancer growth. 2013 3
80 24312439 The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation. 2013 3
81 21954831 Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation. 2012 May 6
82 22335604 Differential activation of signaling pathways by UVA and UVB radiation in normal human epidermal keratinocytes. 2012 Sep-Oct 1
83 22393233 GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. 2012 Jun 15 1
84 22696236 JNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposure. 2012 Oct 1
85 22922995 STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma. 2012 Nov 1
86 22967106 Large hepatitis delta antigen activates STAT-3 and NF-κB via oxidative stress. 2012 Oct 1
87 23125416 CCR1-mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Gα(14/16) signaling and IL-6 release. 2012 Dec 1 1
88 23226414 Protective role of STAT3 in NMDA and glutamate-induced neuronal death: negative regulatory effect of SOCS3. 2012 1
89 23275693 Molecular docking studies on inhibition of Stat3 dimerization by curcumin natural derivatives and its conjugates with amino acids. 2012 3
90 20473906 STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy? 2011 Feb 15 1
91 20978825 Adiponectin reduces C-reactive protein expression and downregulates STAT3 phosphorylation induced by IL-6 in HepG2 cells. 2011 Jan 3
92 20979115 HDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion. 2011 May 15 1
93 21107604 Destructive pulmonary staphylococcal infection in a boy with hyper-IgE syndrome: a novel mutation in the signal transducer and activator of transcription 3 (STAT3) gene (p.Y657S). 2011 May 1
94 21307189 Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta. 2011 May 1
95 21325634 Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways. 2011 Sep 1
96 21398617 CD5 promotes IL-10 production in chronic lymphocytic leukemia B cells through STAT3 and NFAT2 activation. 2011 Apr 15 1
97 21490133 Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis. 2011 Jul 1
98 21619877 The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. 2011 Aug 15 1
99 21801384 Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-κB signaling pathway. 2011 Jul 29 1
100 21810609 Krüppel-associated box-associated protein 1 negatively regulates TNF-α-induced NF-κB transcriptional activity by influencing the interactions among STAT3, p300, and NF-κB/p65. 2011 Sep 1 1