Title : Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion.

Pub. Date : 2017

PMID : 28542650






2 Functional Relationships(s)
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1 In addition, significant phosphorylation of STAT1 (ser 727) and STAT3 (both tyr 705 and ser 727 residues) was also observed, accompanied by a decrease in total STAT1. Serine signal transducer and activator of transcription 3 Homo sapiens
2 These results suggest cross-communication between ERK1/2 and JAK-STAT pathways during EGF-mediated increase in invasion of trophoblast cells; phosphorylation at ser 727 residue of both STAT3 and STAT1 appears to be critical. Serine signal transducer and activator of transcription 3 Homo sapiens