Title : C-C motif chemokine receptor 1 (CCR1) is a target of the EGF-AKT-mTOR-STAT3 signaling axis in breast cancer cells.

Pub. Date : 2017 Nov 7

PMID : 29212252






1 Functional Relationships(s)
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1 Pharmacological inhibition and short hairpin RNA-mediated knockdown experiments showed that AKT-dependent mammalian target of rapamycin (mTOR) activation was involved in the phosphorylation of serine-727 of STAT3, which in turn stimulated the transcription of the CCR1 gene. Serine signal transducer and activator of transcription 3 Homo sapiens