Sulfhydryl Compounds

NFE2 like bZIP transcription factor 2 ; Homo sapiens







60 Article(s)
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1 34517051 Decreased cortical Nrf2 gene expression in autism and its relationship to thiol and cobalamin status. 2022 Jan 1
2 35483566 Evaluation of Oxidative Stress in Degenerative Rotator Cuff Tears. 2022 Apr 25 2
3 33242213 Targeting NRF2 to suppress ferroptosis in brain injury. 2021 Apr 3
4 33298526 Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. 2021 Jan-Jun 2
5 33428920 Effect of combined exposure to environmental aliphatic electrophiles from plants on Keap1/Nrf2 activation and cytotoxicity in HepG2 cells: A model of an electrophile exposome. 2021 Feb 15 1
6 33728852 [Antioxidant status of blood plasma of acutely psychotic patients and its correlation with Nrf2 activation]. 2021 5
7 34301493 Personalized profiles of antioxidant signaling pathway in patients with tuberculosis. 2021 Jul 17 1
8 34943032 The KEAP1-NRF2 System in Healthy Aging and Longevity. 2021 Nov 30 1
9 30961461 Bioavailability of naringenin chalcone in humans after ingestion of cherry tomatoes. 2020 Oct 1
10 31302696 Understanding the role of the cytoprotective transcription factor nuclear factor erythroid 2-related factor 2-lessons from evolution, the animal kingdom and rare progeroid syndromes. 2020 Dec 4 2
11 31518425 From germ cells to neonates: the beginning of life and the KEAP1-NRF2 system. 2020 Feb 1 1
12 32416464 Possible differences in the mechanism of malignant transformation of HaCaT cells by arsenite and its dimethyl metabolites, particularly dimethylthioarsenics. 2020 May 6 2
13 32496983 Oxidative and Nitrosative Stress in the Pathogenesis of Obstructive Lung Diseases of Increasing Severity. 2020 1
14 32717274 Emerging crosstalk between long non-coding RNAs and Nrf2 signaling. 2020 Oct 10 1
15 32787104 CDDO-imidazolide Targets Multiple Amino Acid Residues on the Nrf2 Adaptor, Keap1. 2020 Sep 10 1
16 33276631 NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis. 2020 Dec 2 4
17 30587509 Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization. 2019 Mar 1
18 31288066 Retinoic acid downregulates thiol antioxidant defences and homologous recombination while promotes A549 cells sensitization to cisplatin. 2019 Oct 1
19 31872748 Understanding the Early Biological Effects of Isoprene-Derived Particulate Matter Enhanced by Anthropogenic Pollutants. 2019 Mar 2
20 29717933 The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis. 2018 Jul 1 1
21 28126440 Activation of anti-oxidant Nrf2 signaling by substituted trans stilbenes. 2017 Feb 15 1
22 28441057 Oxidative Stress. 2017 Jun 20 1
23 27638861 Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis. 2016 Dec 1
24 27663261 Nitrosopersulfide (SSNO-) targets the Keap-1/Nrf2 redox system. 2016 Nov 1
25 28123399 The status of Nrf2-based therapeutics: current perspectives and future prospects. 2016 Nov 1
26 25687825 Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability. 2015 Jun 2
27 26115003 Poly-Electrophilic Sesquiterpene Lactones from Vernonia amygdalina: New Members and Differences in Their Mechanism of Thiol Trapping and in Bioactivity. 2015 Jul 24 1
28 26205490 KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity. 2015 Aug 1 2
29 24672634 Lack of association between nuclear factor erythroid-derived 2-like 2 promoter gene polymorphisms and oxidative stress biomarkers in amyotrophic lateral sclerosis patients. 2014 1
30 25140450 Effect of redox modulating NRF2 activators on chronic kidney disease. 2014 Aug 20 2
31 23339572 Chemical reactivity and biological activity of chalcones and other α,β-unsaturated carbonyl compounds. 2013 Aug 1
32 23581983 Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles. 2013 Feb 1
33 26855455 Chemical and biological mechanisms of phytochemical activation of Nrf2 and importance in disease prevention. 2013 1
34 22095074 Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target. 2012 Feb 1
35 22558124 Mechanism of chemical activation of Nrf2. 2012 2
36 22686525 Nrf2: friend and foe in preventing cigarette smoking-dependent lung disease. 2012 Sep 17 1
37 21514635 Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. 2011 Jun 4
38 22118669 HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. 2011 Nov 23 1
39 20026152 Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound. 2010 Apr 1 1
40 20558128 Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling. 2010 Sep 1 1
41 20655236 Inactivation of protein tyrosine phosphatases by oltipraz and other cancer chemopreventive 1,2-dithiole-3-thiones. 2010 Aug 15 1
42 19161347 The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. 2009 Apr 15 1
43 19786557 NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation. 2009 Dec 2
44 17891450 Generation of superoxide from reaction of 3H-1,2-dithiole-3-thione with thiols: implications for dithiolethione chemoprotection. 2008 Jan 1
45 18062931 Keap1 modification and nuclear accumulation in response to S-nitrosocysteine. 2008 Feb 15 1
46 18458837 The cancer chemopreventive actions of phytochemicals derived from glucosinolates. 2008 May 1
47 18684987 Radical-free biology of oxidative stress. 2008 Oct 1
48 19124382 Antioxidant therapeutic advances in COPD. 2008 Dec 1
49 17189831 Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species. 2007 Jan 15 2
50 17376285 Natural dietary anti-cancer chemopreventive compounds: redox-mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells. 2007 Apr 1