Pub. Date : 2021 Jan-Jun
PMID : 33298526
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production. | Sulfhydryl Compounds | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | Using these reagents, here we have determined how enhanced generation of mitochondrial superoxide and hydrogen peroxide, or disruption of mitochondrial thiol homeostasis affect activation of the Nrf2 system in cells, which was assessed by Nrf2 protein level, nuclear translocation and expression of its target genes. | Sulfhydryl Compounds | NFE2 like bZIP transcription factor 2 | Homo sapiens |