Title : Generation of superoxide from reaction of 3H-1,2-dithiole-3-thione with thiols: implications for dithiolethione chemoprotection.

Pub. Date : 2008 Jan

PMID : 17891450






1 Functional Relationships(s)
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1 These findings demonstrate that D3T reacts with thiols, particularly a dithiol, generating superoxide, which may provide a mechanistic explanation for induction of Nrf2-dependent phase 2 enzymes by D3T. Sulfhydryl Compounds NFE2 like bZIP transcription factor 2 Homo sapiens