Title : The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells.

Pub. Date : 2009 Apr 15

PMID : 19161347






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 It has been shown that specific thiol residues of the redox-sensor Keap1 (Kelch-like ECH-associated protein 1) are modified by 15d-PGJ2, leading to activation of the transcription factor Nrf-2 (nuclear factor-erythroid 2 p45 subunit-related factor 2) and up-regulation of genes under control of the electrophile-response element, including HO-1. Sulfhydryl Compounds NFE2 like bZIP transcription factor 2 Homo sapiens