Title : Trigonelline inhibits Nrf2 via EGFR signalling pathway and augments efficacy of Cisplatin and Etoposide in NSCLC cells.

Pub. Date : 2021 Feb

PMID : 33148531






1 Functional Relationships(s)
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1 Nrf2 knockdown experiment in NSCLC cells obliterated the effect of Trigonelline- Cisplatin and Trigonelline-Etoposide combination, indicating the role of Nrf2 inhibition in augmenting drug sensitivity. Cisplatin NFE2 like bZIP transcription factor 2 Homo sapiens