Pub. Date : 2021 Oct 28
PMID : 34320371
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Based on the findings of thirteen tumor entities, we identified three resistance groups, where group 1 (endodermal origin) prominently indicates NRF2-pathway activation, group 2 (mesodermal origin, primordial germ cells) shares elevated DNA repair mechanisms and decreased apoptosis induction, and group 3 (ectodermal and paraxial mesodermal origin) commonly presents deregulated apoptosis induction and alternating pathways as the main cisplatin-induced resistance mechanisms. | Cisplatin | NFE2 like bZIP transcription factor 2 | Homo sapiens |