Title : UFBP1, a key component in ufmylation, enhances drug sensitivity by promoting proteasomal degradation of oxidative stress-response transcription factor Nrf2.

Pub. Date : 2021 Jan

PMID : 33219317






1 Functional Relationships(s)
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1 Experiments using genetic depletion and pharmacological activation in vitro and in vivo demonstrated that UFBP1 enhances the sensitivity of gastric cancer cells to cisplatin through the Nrf2/AKR1C axis. Cisplatin NFE2 like bZIP transcription factor 2 Homo sapiens