| 1 |
34689256 | Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids. | 2022 Jan |
1 |
| 2 |
35074252 | Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation. | 2022 Mar |
2 |
| 3 |
33600998 | The xenobiotic receptors PXR and CAR in liver physiology, an update. | 2021 Jun 1 |
1 |
| 4 |
33636214 | Bile acids and their receptors in metabolic disorders. | 2021 Apr |
1 |
| 5 |
34217791 | Prenatal ethanol exposure increases maternal bile acids through placental transport pathway. | 2021 Jun 30 |
4 |
| 6 |
34444675 | The Role of Vitamin K in Cholestatic Liver Disease. | 2021 Jul 23 |
2 |
| 7 |
31291465 | The gut microbiota at the intersection of bile acids and intestinal carcinogenesis: An old story, yet mesmerizing. | 2020 Apr 1 |
1 |
| 8 |
31604032 | Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets. | 2020 Jan 1 |
2 |
| 9 |
32024859 | Attenuation of bile acid-mediated FXR and PXR activation in patients with Crohn's disease. | 2020 Feb 5 |
5 |
| 10 |
32404746 | Intestinal Inflammation Alters the Expression of Hepatic Bile Acid Receptors Causing Liver Impairment. | 2020 Aug |
6 |
| 11 |
30646906 | Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. | 2019 Jan 15 |
1 |
| 12 |
31106772 | [An overview of bile acid synthesis and its physiological and pathological functions]. | 2019 May 20 |
1 |
| 13 |
31616073 | Bile acids in glucose metabolism and insulin signalling - mechanisms and research needs. | 2019 Dec |
1 |
| 14 |
30453651 | Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases. | 2018 Nov 17 |
2 |
| 15 |
30464886 | Genetic Variations Associated with Anti-Tuberculosis Drug-Induced Liver Injury. | 2018 Jun |
1 |
| 16 |
27871908 | Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor. | 2017 Jan 4 |
2 |
| 17 |
29184608 | Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases. | 2017 Nov 18 |
1 |
| 18 |
27440109 | Effects of soy containing diet and isoflavones on cytochrome P450 enzyme expression and activity. | 2016 Aug |
1 |
| 19 |
27799961 | Heterozygous Inactivation of the Nuclear Receptor PXR/NR1I2 in a Patient With Anabolic Steroid-Induced Intrahepatic Cholestasis. | 2016 Aug |
2 |
| 20 |
27932985 | Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions. | 2016 |
1 |
| 21 |
24905729 | Characterization and treatment of persistent hepatocellular secretory failure. | 2015 Apr |
1 |
| 22 |
25294580 | Pregnane X receptor as the "sensor and effector" in regulating epigenome. | 2015 Apr |
1 |
| 23 |
26416771 | Maternal bile acid transporter deficiency promotes neonatal demise. | 2015 Sep 29 |
1 |
| 24 |
23982684 | Bile acid receptors as targets for drug development. | 2014 Jan |
2 |
| 25 |
24166671 | Pregnane X receptor (PXR)--a contributor to the diabetes epidemic? | 2014 |
2 |
| 26 |
24182399 | Molecular insights into the promiscuous interaction of human pregnane X receptor (hPXR) with diverse environmental chemicals and drug compounds. | 2014 Feb |
2 |
| 27 |
24382005 | Obeticholic acid and budesonide for the treatment of primary biliary cirrhosis. | 2014 Feb |
1 |
| 28 |
24388834 | Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges. | 2014 Feb 12 |
1 |
| 29 |
24859622 | Roles of xenobiotic receptors in vascular pathophysiology. | 2014 |
1 |
| 30 |
25200104 | Targeting FXR in cholestasis: hype or hope. | 2014 Dec |
1 |
| 31 |
23237007 | Pregnane X receptor (PXR) at the crossroads of human metabolism and disease. | 2013 Mar |
1 |
| 32 |
23574760 | Bile acid malabsorption deactivates pregnane X receptor in patients with Crohn's disease. | 2013 May |
3 |
| 33 |
24025090 | Sulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics. | 2013 Nov |
1 |
| 34 |
24329114 | Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily. | 2013 Dec |
1 |
| 35 |
21801835 | FXR and PXR: potential therapeutic targets in cholestasis. | 2012 Jul |
1 |
| 36 |
23000093 | Marine sponge steroids as nuclear receptor ligands. | 2012 Nov |
2 |
| 37 |
23007437 | Ligand- and structure-based pregnane X receptor models. | 2012 |
2 |
| 38 |
21291553 | The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | 2011 Feb 3 |
1 |
| 39 |
21295138 | Nuclear receptor PXR, transcriptional circuits and metabolic relevance. | 2011 Aug |
1 |
| 40 |
21333771 | Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition. | 2011 Apr 25 |
1 |
| 41 |
21395540 | Regulation of hepatic cytochromes p450 by lipids and cholesterol. | 2011 Feb |
2 |
| 42 |
21622216 | Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease. | 2011 Jun 1 |
1 |
| 43 |
21691099 | Pleiotropic functions of the organic solute transporter OstĪ±-OstĪ². | 2011 |
1 |
| 44 |
21742782 | Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor. | 2011 Oct |
2 |
| 45 |
21977915 | Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma. | 2011 Oct 6 |
1 |
| 46 |
19932133 | Bile acid-activated receptors in the treatment of dyslipidemia and related disorders. | 2010 Apr |
2 |
| 47 |
20595403 | Postprandial plasma bile acid responses in normal weight and obese subjects. | 2010 Sep |
2 |
| 48 |
18751930 | Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators? | 2009 Feb |
1 |
| 49 |
19273385 | Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio. | 2009 Jan 1 |
1 |
| 50 |
19297428 | Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner. | 2009 May |
1 |