Bile Acids and Salts

nuclear receptor subfamily 1 group I member 2 ; Homo sapiens







94 Article(s)
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Pub. Year
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1 34689256 Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids. 2022 Jan 1
2 35074252 Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation. 2022 Mar 2
3 33600998 The xenobiotic receptors PXR and CAR in liver physiology, an update. 2021 Jun 1 1
4 33636214 Bile acids and their receptors in metabolic disorders. 2021 Apr 1
5 34217791 Prenatal ethanol exposure increases maternal bile acids through placental transport pathway. 2021 Jun 30 4
6 34444675 The Role of Vitamin K in Cholestatic Liver Disease. 2021 Jul 23 2
7 31291465 The gut microbiota at the intersection of bile acids and intestinal carcinogenesis: An old story, yet mesmerizing. 2020 Apr 1 1
8 31604032 Rifampicin, not vitamin E, suppresses parenteral nutrition-associated liver disease development through the pregnane X receptor pathway in piglets. 2020 Jan 1 2
9 32024859 Attenuation of bile acid-mediated FXR and PXR activation in patients with Crohn's disease. 2020 Feb 5 5
10 32404746 Intestinal Inflammation Alters the Expression of Hepatic Bile Acid Receptors Causing Liver Impairment. 2020 Aug 6
11 30646906 Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. 2019 Jan 15 1
12 31106772 [An overview of bile acid synthesis and its physiological and pathological functions]. 2019 May 20 1
13 31616073 Bile acids in glucose metabolism and insulin signalling - mechanisms and research needs. 2019 Dec 1
14 30453651 Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases. 2018 Nov 17 2
15 30464886 Genetic Variations Associated with Anti-Tuberculosis Drug-Induced Liver Injury. 2018 Jun 1
16 27871908 Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor. 2017 Jan 4 2
17 29184608 Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases. 2017 Nov 18 1
18 27440109 Effects of soy containing diet and isoflavones on cytochrome P450 enzyme expression and activity. 2016 Aug 1
19 27799961 Heterozygous Inactivation of the Nuclear Receptor PXR/NR1I2 in a Patient With Anabolic Steroid-Induced Intrahepatic Cholestasis. 2016 Aug 2
20 27932985 Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions. 2016 1
21 24905729 Characterization and treatment of persistent hepatocellular secretory failure. 2015 Apr 1
22 25294580 Pregnane X receptor as the "sensor and effector" in regulating epigenome. 2015 Apr 1
23 26416771 Maternal bile acid transporter deficiency promotes neonatal demise. 2015 Sep 29 1
24 23982684 Bile acid receptors as targets for drug development. 2014 Jan 2
25 24166671 Pregnane X receptor (PXR)--a contributor to the diabetes epidemic? 2014 2
26 24182399 Molecular insights into the promiscuous interaction of human pregnane X receptor (hPXR) with diverse environmental chemicals and drug compounds. 2014 Feb 2
27 24382005 Obeticholic acid and budesonide for the treatment of primary biliary cirrhosis. 2014 Feb 1
28 24388834 Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges. 2014 Feb 12 1
29 24859622 Roles of xenobiotic receptors in vascular pathophysiology. 2014 1
30 25200104 Targeting FXR in cholestasis: hype or hope. 2014 Dec 1
31 23237007 Pregnane X receptor (PXR) at the crossroads of human metabolism and disease. 2013 Mar 1
32 23574760 Bile acid malabsorption deactivates pregnane X receptor in patients with Crohn's disease. 2013 May 3
33 24025090 Sulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics. 2013 Nov 1
34 24329114 Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily. 2013 Dec 1
35 21801835 FXR and PXR: potential therapeutic targets in cholestasis. 2012 Jul 1
36 23000093 Marine sponge steroids as nuclear receptor ligands. 2012 Nov 2
37 23007437 Ligand- and structure-based pregnane X receptor models. 2012 2
38 21291553 The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. 2011 Feb 3 1
39 21295138 Nuclear receptor PXR, transcriptional circuits and metabolic relevance. 2011 Aug 1
40 21333771 Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition. 2011 Apr 25 1
41 21395540 Regulation of hepatic cytochromes p450 by lipids and cholesterol. 2011 Feb 2
42 21622216 Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease. 2011 Jun 1 1
43 21691099 Pleiotropic functions of the organic solute transporter OstĪ±-OstĪ². 2011 1
44 21742782 Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor. 2011 Oct 2
45 21977915 Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma. 2011 Oct 6 1
46 19932133 Bile acid-activated receptors in the treatment of dyslipidemia and related disorders. 2010 Apr 2
47 20595403 Postprandial plasma bile acid responses in normal weight and obese subjects. 2010 Sep 2
48 18751930 Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators? 2009 Feb 1
49 19273385 Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio. 2009 Jan 1 1
50 19297428 Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner. 2009 May 1