| 51 |
19688601 | Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines. | 2009 Sep |
2 |
| 52 |
20871735 | Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation. | 2009 Jun 1 |
2 |
| 53 |
18096695 | The antiapoptotic role of pregnane X receptor in human colon cancer cells. | 2008 Apr |
5 |
| 54 |
18334180 | [[Inflammation and drug metabolism: NF-kappB and the CAR and PXR xeno-receptors]. | 2008 Mar |
3 |
| 55 |
18537536 | Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential. | 2008 Jun |
1 |
| 56 |
18629309 | Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species. | 2008 Jul |
4 |
| 57 |
18800312 | Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy. | 2008 Oct |
1 |
| 58 |
19018724 | PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics. | 2008 Nov |
1 |
| 59 |
17088262 | PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine. | 2007 Feb |
4 |
| 60 |
17188925 | Pregnane X receptor: promiscuous regulator of detoxification pathways. | 2007 |
2 |
| 61 |
17573484 | Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity. | 2007 Sep |
1 |
| 62 |
17696253 | Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR. | 2007 Aug 21 |
1 |
| 63 |
17963371 | Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. | 2007 Nov 29 |
2 |
| 64 |
16455805 | Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression. | 2006 May |
5 |
| 65 |
16565602 | [Role of PXR and CAR in cholestasis]. | 2006 Mar |
1 |
| 66 |
16749856 | Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations. | 2006 May-Jun |
1 |
| 67 |
16863441 | Functional evolution of the pregnane X receptor. | 2006 Jun |
1 |
| 68 |
16952547 | Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis. | 2006 Sep |
2 |
| 69 |
15331348 | Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription. | 2005 Jan |
8 |
| 70 |
15581595 | Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. | 2005 Jan 15 |
2 |
| 71 |
15670600 | Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis. | 2005 Feb 18 |
4 |
| 72 |
15718292 | Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts. | 2005 Jul |
1 |
| 73 |
15725701 | Nuclear receptors as targets for drug development: regulation of cholesterol and bile acid metabolism by nuclear receptors. | 2005 Feb |
2 |
| 74 |
16101574 | Structure and function of the human nuclear xenobiotic receptor PXR. | 2005 Aug |
1 |
| 75 |
16297466 | Pregnane and Xenobiotic Receptor (PXR/SXR) resides predominantly in the nuclear compartment of the interphase cell and associates with the condensed chromosomes during mitosis. | 2005 Dec 15 |
1 |
| 76 |
15198932 | Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. | 2004 Oct |
2 |
| 77 |
15322103 | Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism. | 2004 Oct 22 |
7 |
| 78 |
15515100 | Modified oligonucleotides containing lithocholic acid in their backbones: their enhanced cellular uptake and their mimicking of hairpin structures. | 2004 Nov 5 |
2 |
| 79 |
12705905 | Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene. | 2003 Apr 25 |
1 |
| 80 |
12805410 | The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity. | 2003 Sep |
5 |
| 81 |
12971975 | ABC transporter regulation by bile acids: where PXR meets FXR. | 2003 Oct |
1 |
| 82 |
14570758 | Induction of ABCC3 (MRP3) by pregnane X receptor activators. | 2003 Nov |
2 |
| 83 |
14683519 | Orphan nuclear receptor modulators. | 2003 |
1 |
| 84 |
11807162 | Regulation of cyp3a gene transcription by the pregnane x receptor. | 2002 |
1 |
| 85 |
11865669 | Structural insights into the promiscuity and function of the human pregnane X receptor. | 2002 Jan |
1 |
| 86 |
11893771 | Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor. | 2002 Mar |
11 |
| 87 |
12016543 | Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR. | 2002 |
2 |
| 88 |
12055601 | Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor. | 2002 Jun |
1 |
| 89 |
12370413 | Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). | 2002 Oct 15 |
2 |
| 90 |
12372848 | The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. | 2002 Oct |
1 |
| 91 |
11248085 | The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. | 2001 Mar 13 |
3 |
| 92 |
11248086 | An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. | 2001 Mar 13 |
4 |
| 93 |
11509573 | Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. | 2001 Oct 19 |
3 |
| 94 |
11607932 | Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism. | 2001 Nov |
3 |